Studies have shown that DNA methylation is critical in the pathogenesis of fibrosis involving multiple organ systems, contributing to significant morbidity and mortality.
Taking these results together, we hypothesized that the Src/Smad1 pathway may be critical in the pathogenesis of proliferative glomerulonephritis.
TLR9 is constitutively expressed on B cells that are critical in the pathogenesis of rheumatoid arthritis [39].
The survival and function of the pancreatic beta-cell is critical in the pathogenesis of all forms of diabetes mellitus [1], [2], [3], [4], [5].
Therefore, it reveals a potential mechanism that is critical in the pathogenesis of AIH by tipping the balance between Th17 and Treg cells.
T cell recognize donor allo-peptides presented by recipient's APCs through the indirect pathway of allorecognition [9], a mechanism that generates indirect pathway CD4 T cells and allo-Abs, both critical in the pathogenesis of CAV [10] [12] and CR [13], [14].
The identified miRNAs and mRNAs may be critical in the pathogenesis of ARDS.
Invasion of fibroblast-like synoviocytes (FLSs) is critical in the pathogenesis of rheumatoid arthritis (RA).
