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This process promotes coordinated extension of FN fibril assembly and cell spreading over time and space.
Nevertheless, a projection map can be helpful to discuss the potential mechanisms that underline the coordinated extension of pseudopodia.
Cell migration requires the coordinated extension of membrane protrusions, formation of transient adhesions along the membrane extensions, and NMMII-dependent detachment of the cell rear [43].
Cell motility requires the coordinated extension of membrane protrusions, formation of transient adhesions, and myosin-dependent detachment of the cell rear.
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In bacteria such as E. coli, growth must be coordinated with extension so that width is maintained as cell length increases.
In wild type embryos, muscle cells appear to be actively driving tail extension in cooperation with notochord cells, through their coordinate elongation, while in muscle cells expressing Bix1, muscle elongation is impaired, thus constraining tail extension [22].
This result indicates that the WT STA cells coordinate the extension and retraction of protrusions with cell movement and that the PI3K inhibition and pten depletion causes the loss of such coordination.
Thus, Rab25 can coordinate process extension, by recycling unligated integrin to the cell front, with retraction by recycling active integrins to the cell rear where they can promote signals for forward movement.
Generic coordinate along lamp extension (mm).
Non-dimensional coordinate along lamp extension in a transversal plane perpendicular to cylinder axis.
Sparsely sampled data, interpolation, extension, coordinate transformation and several algorithms are illustrated in Figure 1.
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