confirmation of efficacy

USAGE SUMMARY

The phrase "confirmation of efficacy" is correct and usable in written English.
It can be used in contexts where you are discussing the validation or proof of the effectiveness of a treatment, product, or intervention. Example: "The study provided a confirmation of efficacy for the new drug in treating the disease."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

15 human-written examples

Information about clinical effect size and dose response is subsequently obtained in the phase IIB 'learn phase' of the second learn-confirm cycle, with final confirmation of efficacy and safety in larger numbers of patients in phase III studies.

Alzheimer's Research and Therapy

The drug development process can be streamlined by combining the traditionally separate stages of dose-finding (Phase IIb) and confirmation of efficacy and safety (Phase III) using an adaptive seamless design.

Pulmonary Pharmacology & Therapeutics

Apart from the confirmation of efficacy, the acquired information may help to investigate the shape and location of the dose-response curve, the choice of an appropriate therapeutic starting dose, the identification of optimal strategies for individual dose adjustments, and the determination of a maximal dose beyond which additional benefit is unlikely to be obtained.

Pharmacology & Therapeutics

Water displacement leg volumetry is a highly reproducible method, allowing the confirmation of efficacy of vasoactive substances.

BMC Medical Research Methodology

Moving directly to deduction (confirmation) of efficacy is efficient, in the sense that it is rapid and of low cost.

CPT: Pharmacometrics and Systems Pharmacology

Although rationale and fascinating, this proposal need to be assessed with proper clinical trials and no implementation should be considered without preliminary confirmation of efficacy and safety.

Diabetes Care

Human-verified similar examples from authoritative sources

Similar Expressions

45 human-written examples

It is equally important to point out that with the lack of data of an incremental mortality benefit, routine use of V2 receptor antagonists will unlikely be justified especially with the likely cost differential compared to loop diuretics, except in aforementioned subgroups that would need careful confirmation of efficacies and economic justification.

Core Evidence

The confirmation of the efficacy of Onabotulinumtoxin A at the dose of 195 U in Medication Overuse Headache came from the largest post-marketing two years open-label prospective study by Negro et al. [146].

The Journal of Headache and Pain

Development of a new phytosanitary treatment to augment the existing toolbox requires confirmation of treatment efficacy for relevant life stages of quarantine pests, identified by a formal pest risk assessment process.

New Zealand Journal of Forestry Science

Although confirmation of the efficacy of this pharmacological approach awaits completion of large clinical trials, the adjuvant use of these compounds is common in patients that do not meet targeted reductions of lipoproteins while taking statins [6] [10].

Plosone

For confirmation of transfections efficacy, the AllStars cell death control (Qiagen) was used.

British Journal of Cancer

Expert writing Tips

Best practice

When writing scientific documents, use "confirmation of efficacy" to clearly indicate that the effectiveness of a treatment or intervention has been verified through rigorous testing. Use the phrase to add authority and precision to your findings.

Common error

Avoid using "confirmation of efficacy" when you are actually describing initial findings or preliminary results. This phrase implies that effectiveness has been firmly established, not merely suggested. If the evidence isn't conclusive, opt for wording like 'initial indications of efficacy' or 'preliminary evidence suggesting efficacy' instead.

Linguistic Context

The primary grammatical function of "confirmation of efficacy" is to act as a noun phrase. It typically serves as the subject or object of a sentence, denoting the act or state of verifying the effectiveness of something, as evidenced by Ludwig's examples.

Expression frequency: Uncommon

Frequent in

Science

95%

News & Media

3%

Formal & Business

2%

Less common in

Encyclopedias

0%

Wiki

0%

Reference

0%

Ludwig's WRAP-UP

In summary, "confirmation of efficacy" is a noun phrase used to express that the effectiveness of something has been verified, as also stated by Ludwig. Predominantly found in scientific and medical literature, it carries a formal tone and is crucial for objectively reporting established results. While grammatically correct and widely accepted, it's vital to use this phrase only when actual effectiveness has been proven. Alternative phrases include "validation of effectiveness" and "proof of effectiveness", offering nuanced variations in meaning. The phrase's prevalence in authoritative sources reinforces its reliability and appropriateness for formal writing.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

validation of effectiveness

Replaces "confirmation" with "validation", emphasizing the act of proving effectiveness.

verification of effectiveness

Substitutes "confirmation" with "verification", highlighting the process of checking or proving something's truth.

proof of effectiveness

Emphasizes the evidence that demonstrates the effectiveness.

establishing efficacy

Focuses on the act of setting up or demonstrating efficacy.

efficacy confirmation

Inverts the phrase structure while retaining the core meaning.

demonstrating efficacy

Highlights the action of showing or proving that something works.

efficacy validation

Similar to "validation of effectiveness" but with a different word order.

corroboration of efficacy

Uses "corroboration" to suggest supporting evidence for efficacy.

substantiation of efficacy

Replaces confirmation with a more formal term, "substantiation".

ascertainment of efficacy

Uses "ascertainment" to emphasize the process of finding something out for certain.

FAQs

How is "confirmation of efficacy" typically used in clinical trials?

In clinical trials, "confirmation of efficacy" refers to the stage where a treatment's effectiveness has been rigorously tested and proven, often in Phase III trials. It indicates the treatment has met predefined endpoints for success and is considered effective for its intended use.

What are some alternatives to "confirmation of efficacy"?

You can use alternatives like "validation of effectiveness", "proof of effectiveness", or "establishing efficacy" depending on the specific nuance you want to convey.

What does "confirmation of efficacy" mean in the context of drug development?

In drug development, "confirmation of efficacy" signifies that a drug has successfully demonstrated its ability to produce the desired therapeutic effect in a controlled clinical setting. This confirmation is a crucial step before regulatory approval and market release.

Is there a difference between "confirmation of efficacy" and "demonstration of efficacy"?

"Demonstration of efficacy" implies showing or illustrating that a treatment works, while "confirmation of efficacy" suggests that the effectiveness has been rigorously proven and verified through testing. "Demonstrating efficacy" might refer to earlier-stage findings, while confirmation requires more robust evidence.