cell-based assays

USAGE SUMMARY

The phrase "cell-based assays" is correct and usable in written English.
You can use it when describing experiments involving cells in a laboratory setting, such as to analyze the effects of a drug on cancer cells. For example, "Researchers performed cell-based assays to assess the efficacy of the new drug in treating cancer."

✓ Grammatically correct

Science

Academia

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

Cell-based assays based on disease-specific phenotypes, such as cell proliferation, migration, and invasion in the case of cancers, have been used to identify lead compounds1, 2. However, elucidation of the MoA and molecular targets of compounds obtained by phenotypic screening remains challenging, and is therefore a rate-limiting step for drug discovery using cell-based assays.

Nature

Sticker, D. et al. Zirconium dioxide nanolayer passivated impedimetric sensors for cell-based assays.

Nature

A.I., F.M.N.K., and J.A. performed and oversaw the cell-based assays.

Nature

S.C., J.-Y.H., D.A.A., B.L. and J.C. developed and performed cell-based assays.

Nature

They virtually screen 1.6 million compounds and predict 25 Olfr73 agonists, 17 of which are validated by cell-based assays.

Nature

The N-terminal domain of CCBE1 affects the distribution and activity of pro-VEGF-C in cell-based assays.

Nature

Cell-based assays are further supported by the addition of a carbon dioxide incubator to the Sciclone pipetting deck.

Stanford University

designed and performed DEER experiments; X.G., Y.Y., P.L. and Y.J. performed cell-based assays; G.Z. and X.M. helped with data collection.

Nature

For cell-based assays, recent reports highlight the drive towards primary cell types, endogenous target expression and label-free systems3,4,5,6.

Nature

Taken together, these data show that an HD-specific property exists in patient CSF that can be monitored in relatively simple cell-based assays.

Nature

Previously, we identified two thiazolothiazepines lead IN inhibitors with antiviral activity in cell-based assays.

Bioorganic & Medicinal Chemistry

Expert writing Tips

Best practice

When describing the specific type of "cell-based assays", be as precise as possible (e.g. "cell proliferation assays", "cytotoxicity assays").

Common error

Do not use "cell-based assays" as a substitute for in vivo studies when referring to the overall effectiveness of a compound or treatment. Cell-based assays are useful for initial screening, but further testing is needed to validate the findings.

Linguistic Context

The phrase "cell-based assays" functions primarily as a noun phrase, often serving as the object of a verb or as a modifier in scientific writing. Ludwig confirms this usage through numerous examples of its application in scientific research.

Expression frequency: Common

Frequent in

Science

77%

Academia

21%

Formal & Business

2%

Less common in

News & Media

0%

Encyclopedias

0%

Wiki

0%

Ludwig's WRAP-UP

In summary, "cell-based assays" is a common and grammatically correct term used extensively in scientific and academic writing to describe experiments involving cells. Ludwig AI confirms its validity and provides numerous examples from authoritative sources. This phrase is most frequently found in the context of science and academia and is used to describe research methodologies and results. When using this phrase, ensure accuracy by specifying the type of assay being conducted and avoid overgeneralizing its applicability.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

cellular assays

This alternative is a more concise term to indicate the assay is performed at cellular level.

in vitro cell assays

This alternative emphasizes the "in vitro" nature of the assay.

cell-culture assays

This alternative highlights the cell culture technique used.

biological assays using cells

This alternative is more descriptive and specifies the biological nature of the assays.

cellular activity assays

This alternative highlights that the assays test the activity of the cells.

cell viability assays

This alternative focuses on assays to test how viable cells are.

phenotypic assays

This alternative emphasizes the assay to determine the physical characteristics of a cell.

in cellulo assays

This alternative uses a Latin term to highlight the fact that the assays are performed in living cells.

cellular response assays

This alternative points out that the assays are used to analyze the response of cells.

assays involving cell lines

This alternative specifies that the assays use cell lines.

FAQs

How are "cell-based assays" used in research?

"Cell-based assays" are used in a wide range of research applications, including drug discovery, toxicity testing, and basic biological research. They allow scientists to study cellular responses to various stimuli in a controlled environment.

What are the advantages of "cell-based assays" over other methods?

"Cell-based assays" offer several advantages, including the ability to study complex biological processes at the cellular level, the potential for high-throughput screening, and reduced reliance on animal testing. However, it's hard to predict clinical behavior from "cell-based assays".

What are some alternatives to "cell-based assays"?

Alternatives to "cell-based assays" include cell-free biochemical assays, in vivo studies, and computational modeling. The choice of method depends on the specific research question and the desired level of complexity.

How do "cell-based assays" compare to biochemical assays?

While biochemical assays analyze molecular interactions, "cell-based assays" assess the effects of those interactions within a cellular context. "Cell-based assays" offer a more physiologically relevant environment but can be more complex to perform and interpret than biochemical assays.