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Exact(6)
We calculated similarities between drugs and between proteins in the same way as for the four gold standard datasets.
The similarity of a bug report and a source file is given by the sum of the calculated similarities.
In contrast, a larger probe radius would include more of the molecules with less global USR similarity, which in turn would increase the dependence of the four pharmacophore moments on the calculated similarities.
If a PPI (test instance) was judged as positive in a process, we calculated similarities between the feature vector of the test and that of each positive.
By evaluating the correlation coefficient between the calculated similarities and the results from MEGA [ 9], the proposed method FPE achieves higher correlation coefficients than two recently-developed alignment-free methods [ 14, 18] and BLASTN [ 7].
To test if the converted regions themselves influenced the higher similarity in the conversion group, we also calculated similarities of genes in conversion pairs, omitting the converted regions from the analysis.
Similar(54)
As last experiment for the by-hand approach, we calculated similarity rankings with the ECFP similarity and also with an extended version of the ECFP similarity.
We then calculated similarity scores for these aligned structures.
We calculated similarity matrices using an aligned cumulative dataset containing all of the OTUs together and separately for OTUs belonging to each of the clades.
For these pairs, we subsequently calculated similarity in structure and stereochemistry.
In light of these difficulties, attempts have been made to replace calculated similarity values for activity cliff assessment by structurally more conservative and intuitive similarity criteria.
Related(19)
calculated specificities
calculated comparisons
calculated arrangements
calculated attributes
calculated ways
calculated characteristics
reflected similarities
calculated traits
calculated agreements
compute similarities
deliberate similarities
computing similarities
calculates similarities
calculated risks
calculated tons
calculated timings
calculated metrics
calculated smirks
calculation similarities
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