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Inhibition of Praf2-induced PARP cleavage was also prevented by the concomitant expression of Bcl-2 (data not shown).

We therefore tested if Praf2 overexpression could induce cell death, and if this could be blocked by the concomitant expression of Bcl-xL or the Bcl-xLΔTM mutant that was shown to be unable to bind to Praf2.

This is supported by the concomitant expression of the two ABC-G proteins have with ZHD101.

This was accompanied by the concomitant expression of a truncated Vps15 form of 100 kDa.

Importantly, these phenotypes were alleviated by the concomitant expression of AOX, even at relatively modest levels, e.g. tub-AOX rescue of the levy phenotype (Fig.  6A).

Even though a few aneuploid cells were observed at the latest passages (PD 74 and 87), Burchelli's zebra fibroblasts immortalized by the concomitant expression of h TERT and h TERC kept the phenotype most similar to normal cells.

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By sequestering LTB4, Ir-LBP prevents LTB4-dependent transmigration of neutrophils, and probably prevents the concomitant expression of proteins induced by LTB4, both in neutrophils and endothelial cells.

Whether signalling is enhanced or suppressed by Sdc might depend on Slit/Robo and Sdc levels, and also on the concomitant expression of other heparan sulphate proteoglycans.

We recently showed, by the hierarchical clustering of S100 gene expression in 22 breast cancer SAGE libraries, that one group with a distinguishable S100 gene expression profile was characterized by the high concomitant expression of psoriasin, calgranulin A and calgranulin B [ 27].

Although we could not determine why sIL-6R detection was reduced by the concomitant enhanced expression of IL-6 in cancer cells' cytoplasm, it may be hypothesised that the increased release of sIL-6R and sgp130 from cancer cells induced increased binding of sIL-6R by both the soluble and membranous forms of gp130 in cancer stroma, resulting in a decrease of sIL-6R in cancer tissue.

In other studies, we found that toxic inhibition of complex III (cIII) by antimycin or cIV by cyanide, or phenotypes resulting from mutations or knockdown of cIV subunits or the cIV assembly factor Surf1 in Drosophila, could be mitigated by concomitant expression of the mitochondrial alternative oxidase (AOX) from Ciona intestinalis (Fernández-Ayala et al. 2009; Kemppainen et al. 2014).

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