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However, significant differences exist as well, possibly explained by technical differences in both collection and analysis.
Comparing gene expression profiles from multiple experiments is notoriously difficult and typically any true similarities are swamped by technical differences in microarray vendor, normalization strategies and analytical approach.
Discrepancies may be explained by technical differences in the viral detection methods or differences in sexual behavior in the study populations.
This variance of BMP expression levels in OA tissue in comparison with normal or RA synovial tissue may be explained by technical differences in sensitivity and resolution between PCR and microarray hybridization.
We acknowledge that our unpublished experiment may have been confounded by technical differences in processing of the patient and control samples, as well as by the age difference between cases and controls.
A number of studies have published microarray data of glucocorticoid-induced genes in lymphoid cells, but comparison of the data is complicated by technical differences in platform and chip type.
Similar(53)
This discordance could be explained by the number of samples considered and by technical differences.
Discrepancies between the expression levels of DEGs identified in the microarray and by RT-qPCR could be related to technical differences in the sensitivity and specificity between the methods, and biological variations, i.e., differences between the genotypes used.
These two differences could be explained by the spindle morphology being perturbed by the increased microtubule polymer in cdc25.22 fission yeast cells or the technical differences in the electron microscopy.
A number of technical differences in the design of the experiments we conducted and those conducted by these investigators can perhaps reconcile the apparent discrepancies in our results.
Finally, technical differences in the methodologies used may be contributing to these differences.
Related(16)
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