Sentence examples for by technical difficulties in from inspiring English sources
Although recent studies have provided further insight to mammalian heart development, our understanding of this complicated process is incomplete; elucidation of these processes has been greatly hampered by technical difficulties in studying early mammalian development in utero.
The use of plasma estrogens (estradiol and estrone) to evaluate the activity of aromatase inhibitors is hampered by technical difficulties in measuring very low postmenopausal estrogen levels [ 23].
Despite these findings, attempts to discover tumor EC markers have always been hampered by technical difficulties in isolating functionally intact and phenotypically stable EC from tumor tissues.
Progress for plant species has been limited by technical difficulties in extracting aDNA from the sort of fossils commonly used in paleoecological studies, though recent advances in this area show promise [ 29, 30].
This can be explained by technical difficulties in the complete removal of tumor tissue when performing intralesional treatment and the lack of adequate applicable local adjuvants, in the presence of soft tissue extension.
The use of plasma oestrogens (oestradiol and oestrone) to evaluate the activity of aromatase inhibitors is hampered by technical difficulties in measuring very low postmenopausal oestrogen levels (Geisler et al, 2002, 2008; Dixon et al, 2008).
Further functional characterization of LRRK2-DVL interactions is currently hindered by technical difficulties encountered in purifying intact DVL proteins, reproducibility and sensitivity of LRRK2 GTPase and kinase assays, and the lack of commercially available antibodies against LRRK2 and DVL1-3 prothats that function in immunoprecipitation experiments.
The set was so epic in fact, that Dillon Francis' set, one plagued by technical difficulties, sounded subdued in comparison.
Moreover, the observed differences could be caused by technical difficulties, including mistakes in interpretation of visualized bands and insufficient separation of PCR fragments in poliacrylamide gel, or by difficulties of the PCR amplifying large products itself.
In our study, matK provided among the highest species resolution of any single region; however, its success is complicated by the technical difficulties in retrieving sequences (Table 1).
Magnifying endoscopes have reportedly been useful in overcoming this difficulty [ 11, 12] but their use is limited by the technical difficulties in manipulating the scopes.
