Sentence examples for by several pathways including from inspiring English sources

In Arabidopsis thaliana, this transition is genetically controlled by several pathways, including the autonomous pathway, the photoperiod pathway and the vernalization pathway, which form a regulatory network [1], [2].

Moreover, HES1 is regulated by several pathways, including Hedgehog [ 37], ATF2 [ 38], and signalling through JNK1 [ 39].

Signaling downstream from the chemokine receptor-ligand interaction is mediated by several pathways including G protein-coupled receptor signaling, Src-family signaling, and MAPK family signaling [ 16, 17].

In contrast, Ca2+-induced autophagy can be mediated by several pathways including calmodulin-dependent kinase kinase β, calmodulin-dependent kinase I, protein kinase C θ, and/or extracellular signal-regulated kinase.

Our results are consistent with previous research which has shown that TGF-β signaling mediates the cellular migration of breast cancer cells by several pathways including ERK1/2 activation [ 42].

The kinase shaggy/GSK-3β is one of the most highly connected genes in the network and is regulated by several pathways, including PI3K and Wnt, although no other Wnt pathway components were identified functionally or computationally.

Together, these findings raise the possibility that Mta1 may play a significant role in protecting regulation of innate immune response by directly modulating several pathways including NF-κB signaling [43].

Thrombin is known to have a significant remodelling effect over endothelial junctions, by acting through several pathways including small GTPases for review [ 36].

In these models, PyMT drives transformation of MECs by signaling through several pathways, including Src, Ras, and phosphoinositide 3-kinase [ 18– 21], resulting in a phenotype similar to ErbB2/Neu-induced tumors [ 7, 22, 23].

Another oncogenic microRNA – miR-21 – was described as playing a critical role in the development and progression of lung cancer by regulating multiple genes controlling several pathways including JAK/STAT, MAPK, PPAR signaling and cell cycle related pathways, based on a systematic analysis of literature and gene network studies (Frezzetti et al., 2011; Guan et al., 2012; Hatley et al., 2010).

As pharmacological manipulation of sirtuins by resveratrol has been proposed to activate several pathways, including autophagy, these studies are of particular interest from a potential therapeutic standpoint.