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Mortality amongst HIV-negative individuals in the two earlier phases, and mortality among PLWH in each ART phase, were compared by fitting an interaction term in the model between HIV status and ART phase.

We evaluated the possible modifying effect of baseline vasomotor symptoms on effects of treatment at one year in health related quality of life by fitting an interaction term(s).

We also formally tested for interaction between maternal age and admission by fitting an interaction term between them and conducting a likelihood ratio test at the 5% level of significance.

Finally, we tested for a difference in these three slopes (of the linear estimates for APOE genotype by smoking status: present, past, never smoking) by fitting an interaction term between APOE genotype status and smoking status in the logistic regression model and using likelihood ratio test to investigate whether a simpler model (without the interaction term fitted) better explained the data.

Similar(56)

No hospital's SHMI would change by more than 5% as a result of fitting the covariates deprivation score and number of previous emergency admissions or fitting an interaction with age and comorbidity (fig 1).

Evaluation of association rate constants (kon), dissociation rate constants (koff) and equilibrium dissociation constants (KD = kon/koff) was performed by fitting a 1∶1 interaction model (Langmuir binding model), removing the background from the reference flow channel by Biacore T100 software v1.1 for RSV evaluations and Biacore 3000 Software v4.1 for the Influenza H5 evaluations.

Finally, a formal statistical analysis of the differences in preferences for job posting attributes between nursing students and practicing nurses was conducted by fitting a mixed logit interaction model.

For age, educational level, and occupational position, a P value for trend across the categories was also calculated by fitting a linear group interaction term with rank of MET-hours/week.

Although the study was not powered for subgroup analyses, we went on to assess treatment effects on the primary outcomes by season of conception (wet-hungry compared with dry-harvest) by fitting a season × treatment interaction term into the models.

We proceeded by fitting a model with possible interactions between the HLA-A and HLA-DRB1 loci.

This will be achieved by fitting a subgroup by randomised group interaction term to the multilevel model.

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