Here we investigate the action of NAX-5055 athehe cellular level by determining its effects on excitatory and inhibitory neurotransmission, i.e. vesicular release of glutamate and GABA, respectively, in cerebellar, neocortical and hippocampal preparations.
Our experiments on cells isolated from Pb-exposed animals focus on the mechanism by which Pb inhibits fracture healing by determining its effects on progenitor cells.
We were also interested in assessing the mode of action of this compound in these cells by determining its effects on drug transport across the cell membrane.
Herein, we have further defined the mechanistic basis of persin-induced cytotoxicity and synergy with 4-OHT in human breast cancer cells, by determining its effects on ERS pathways in 4-OHT-sensitive and -resistant cell lines.
The volume fraction of Pu in the mixture is raised from 0 to 40% stepped by 10% to determine its effect on the B/T.
To gain further insights into the mode of cell death caused by S. grandiflora methanolic fraction, we determined its effect on the DNA fragmentation, a widely used technique for the detection of apoptosis.
