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Neuroimaging studies have yielded mixed results on regional brain volume differences between depressed and non-depressed AD patients.
However, no VBM study has directly compared brain volume differences between the subtypes of AN and examined the effect of differential levels of dietary restraint on brain volume.
Additionally, in contrast to the previous review, we conduct extensive meta-analyses on global and regional brain volume differences between AN versus healthy controls.
Nevertheless, our preliminary findings, especially regarding brain volume differences between the subtypes of AN, provide regions of interest for future studies.
It is important to notice, however, that the discriminative morphological pattern generated by the classifier reflects a set of brain regions needed for between-group classification, but not necessarily all areas of regional brain volume differences between the groups under study.
Similar(55)
Importantly, there were no global brain volume differences detectable between GG and AA subjects that could have accounted for DTI results (p > 0.05 for all comparisons; Fig 3H).
The sex-related differences in baseline brain volumes between groups observed in our study were comparable to the differences found in our baseline study in which between-group brain volume differences were also only significant for female participants (7).
The relationship suggested by our results between brain volume differences, differences in functional connectivity in the language network and language function in PT children supplements previous volumetric imaging studies that evaluated the cerebral structural sequelae of PT birth.
To discern whether these associations between ZNF385D and fiber tract volumes reflect global brain volume differences among genotype, we next examined the relationship of ZNF385D with both total brain segmentation and total cortical volumes.
In AN, brain volume differences were found in appetitive, somatosensory and top-down control brain regions.
We were unable to find any significant main effects or interaction between the BDNF p.Val66Met, levels of childhood trauma, and AUD resulting in structural brain volume differences.
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