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No differences were found in mean hearing levels between the randomized and nonrandomized children: in both the randomized and nonrandomized children ventilation tubes improved the hearing level, especially after 6 months.
The results showed that the combined approach (MSC + CVI) was associated with the highest proportion of drug-negative urine samples during both the randomized and 3-month follow-up arms of the evaluation.
After generating 1000 replicates for each gene, we then evaluated ENC for both the randomized and observed data.
However, in both the randomized and open-label phases of the pivotal multi-center trial, methylnaltrexone produced rescue-free laxation in only about half the patients [ 9].
We conducted a sensitivity analysis by introducing a range of standard error values for the mean difference between baseline and after 12 months of therapy from both the randomized and observational studies, since assumptions were necessary at this step as described in Materials and methods.
Similar(55)
Another important limitation of both the randomized trials and the observational studies examining bundled GDT is that multiple interventions occurred that could potentially influence patient outcome.
Any answer other than the one that would suggest selection bias due to the small number of subjects enrolled in both the randomized clinical trial and the stable isotope infusion protocols and the retrospective nature of the examination would invoke a new paradigm.
Corticosteroid treatment was permitted in both the randomized clinical trials and observational studies.
In general, when basal insulin was added to existing GLP-1 RA therapy there was improvement in glycaemic control with no change in weight or minimal weight gain in both the randomized trials 54– 58, 59, 59 and the observational studies 45, 46.
Thus, both mutations seem to establish stabilizing patches at the base of the randomized and elongated EF loop.
In the UK all of the subjects, both randomized and non-randomized controls will be flagged by the UK Office for National Statistics (ONS) in order to track them through the UK National Health Service database and to permit tracing and outcome assessment by local consultants and to receive notifications of deaths.
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