Sentence examples for both positional and functional from inspiring English sources

These findings combined make MDR1 an excellent both positional and functional IBD candidate gene.

Genes listed can therefore be considered as both positional and functional candidate genes.

Additional SNPs, especially those non-synonymous SNPs in the above mentioned three RGAs, would provide both positional and functional variation sites for further characterization of major gene resistance against C. ribicola.

Consequently, genes with both positional and functional evidence for a role in disease aetiology can reveal the pathways and early precursors or biomarkers underlying the pathogenesis of type 1 diabetes.

The QTL regions that we identified contain many genes with functions that suggest a role in response to heat stress and, thus, these genes are both positional and functional candidates.

Considering their intimate interactions with opioid receptors (mainly the mu-receptor) and their gene locations (RGS17 is in the vicinity of OPRM1 and RGS20 is in the vicinity of OPRK1), the two genes (RGS17 and RGS20) encoding them are both positional and functional susceptibility candidate loci for SD.

Therefore, AMACR is both a positional and functional candidate gene for susceptibility to schizophrenia.

Genome-wide linkage analysis has identified several susceptibility loci for the ASDs, and positional and functional candidate genes have been identified that may represent susceptibility genes for the ASDs.

Therefore, we considered PITX3 a positional and functional candidate gene.

DNAJB1 was also selected as a positional and functional candidate.

Therefore, we considered NDRG1 a positional and functional candidate gene and performed mutation analysis in affected and control Greyhounds.