binding affinities of both

USAGE SUMMARY

The phrase "binding affinities of both" is correct and usable in written English.
It can be used in scientific or technical contexts, particularly in discussions about molecular interactions or biochemistry. Example: "The study measured the binding affinities of both the enzyme and the substrate to determine their interaction strength."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

8 human-written examples

Finally, peroxisome proliferator activated receptor gamma (PPARγ) binding activity was measured to check the binding affinities of both TGZ and TSN.

Toxicology Letters

We find that the binding affinities of both RecBC and RecBCD for a DNA end are unaffected upon substituting PEG for the ssDNA between the sixth and the final two nucleotides of the 3′- dT n tail.

Journal of Molecular Biology

It comes as a surprise that the mutation of Glu119 that can form strong H-bonds with the inhibitors in the wild-type protein does not have direct impact on the binding affinities of both OTV and PRV due to the regulation of the strong unfavorable polar desolvation energies.

Antiviral Research

To further determine the specific binding affinities of both native CN and VCN to purified (αvβ3 and αvβ5) or recombinant (α5β1) functional integrins, we measured these interactions in solution by fluorescence polarization.

Plosone

Since eIF3f serves as a connecting platform between mTOR-raptor and S6K1 in muscle cells (Figure 2) and mutation of the C-terminal lysines in eIF3f increases phosphorylation of S6K1, we assessed the binding affinities of both eIF3f wt and mutant eIF3f K5–10R proteins with S6K1 and mTOR-raptor.

Plosone

The binding affinities of both variants to IL-13Rα1 were unchanged compared to wild-type IL-13 (data not shown).

BMC Biology

Human-verified similar examples from authoritative sources

Similar Expressions

52 human-written examples

We investigated the possibility of separated coating formation of Al as Al2O3 and F as LiF from AlF3 using density functional theory calculation, which suggests a favorable binding affinity of both Al2O3 and LiF phases to the OLO surface to support the preferable formation of coating layer of Al2O3 and LiF.

Electrochimica Acta

The present study aimed at the establishment of two novel experimental approaches for the assessment of binding affinity of both, radiolabelled and non-labelled compounds targeting the A3R, based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics.

EJNMMI Research

In the present study, we successfully designed and established two experimental approaches for the reliable in vitro assessment of binding affinity of both, radiolabelled and non-labelled compounds, based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics.

EJNMMI Research

Twelve classical phenotypes with high content validity map to the Comt locus (p<0.02, Table S2), including binding affinity of both dopamine receptors (DRD1 and DRD2) in caudate, nucleus accumbens, ventral tegmental area, and prefrontal cortex [19].

Plosone

On the other hand the human receptor binding affinity of both CkPA04-TLS (Kd' ∼3 pM) and CkPA04-RTLS (Kd' ∼8 pM) were several fold higher than that of CkPA04-LS and in the same range as that of Alb58 HA.

Plosone

Expert writing Tips

Best practice

When discussing molecular interactions, clearly define what "both" refers to in order to avoid ambiguity. For example, specify "the binding affinities of both the enzyme and the substrate."

Common error

Avoid using "binding affinities of both" without providing specific context or measurable data. Vague statements can weaken the impact of your writing. Instead of simply saying "the binding affinities of both were significant", quantify the affinities and compare them.

Linguistic Context

The phrase "binding affinities of both" functions as a noun phrase, often serving as the subject or object of a sentence. It refers to the strength of interaction between two entities, commonly used in scientific contexts. As Ludwig AI confirms, it's a standard and usable phrase.

Expression frequency: Uncommon

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

In summary, "binding affinities of both" is a grammatically sound and usable phrase, predominantly found in scientific contexts. Ludwig AI validates its correctness and common use in discussing molecular interactions. When using the phrase, ensure you clearly define what "both" refers to, and quantify the affinities for greater impact. While alternatives like "binding strength of both" and "interaction strength of both" exist, "binding affinities of both" is the most precise in many scientific discussions. Proper quantification and clear context will help enhance the clarity and impact of your scientific writing.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

binding strength of both

Substitutes "affinities" with "strength", providing a more direct and less technical term.

relative binding affinities of both

Includes "relative" emphasizing a comparison between the two affinities.

ligand binding affinities of both

Adds 'ligand' before the 'binding', making it more explicit.

receptor binding affinities of both

Adds 'receptor' before the 'binding', making it more explicit.

the two binding affinities

Uses definite article and replaces 'both' with 'the two' providing a more formal tone.

the respective binding affinities of both

Adds 'respective' specifying that affinity belongs to each of the two entities.

affinity of both for binding

Reverses the order and uses "affinity of" instead of "binding affinities", emphasizing the affinity rather than the binding itself.

the binding affinity of each

Focuses on individual affinity rather than the compound affinity.

interaction strength of both

Replaces "binding affinities" with "interaction strength", broadening the scope from just binding to overall interaction.

binding capacity of both

Changes "affinities" to "capacity", focusing on the amount that can be bound rather than the strength.

FAQs

How is "binding affinities of both" used in scientific writing?

In scientific writing, "binding affinities of both" is used to compare how strongly two different substances or molecules bind to a target. For example, comparing the "binding affinities of both" a drug and a natural ligand to a receptor.

What does "binding affinities of both" imply about the compared substances?

The phrase implies that the substances or molecules being compared are capable of binding to a common target, and the writer is interested in comparing the strength of these interactions. Understanding these "binding affinities of both" helps in understanding biological processes.

What are some alternatives to "binding affinities of both"?

You can use alternatives like "binding strength of both", "relative binding affinities of both", or "interaction strength of both" depending on the specific context and desired emphasis.

How do I quantify the "binding affinities of both" in my research?

Quantifying the "binding affinities of both" usually involves techniques like surface plasmon resonance (SPR), isothermal titration calorimetry (ITC), or enzyme-linked immunosorbent assays (ELISA). These methods provide quantitative data on the strength of the binding interactions.