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Second, some were completed by three lead authors between the five studies [35 38], which may contribute to publication bias.
Furthermore, as has been previously shown for other microarray datasets [35], there was very little overlap between the five studies despite the similarities in study design.
There was good agreement between the five studies.
The heterogeneity (I) between the five studies was 59.5% (P = 0.04) (Fig. 2 A).
There was no evidence for the presence of significant heterogeneity between the five studies (Q = 4.86, P = 0.30; I = 18%).
Substantial clinical and methodological heterogeneity between the five studies in this review led to an inconclusive answer to the question whether the use of antipsychotics is associated with the incidence of MI in adults.
Similar(53)
Why might account for the discrepancy between the two studies?
In contrast, N100 findings differ between the two studies.
What causes the apparent discrepancy between the two studies?
For men aged 65-69 the rate of new cases had more than halved between the two studies.
There were also stark differences in the reported strain-load relationship of the Sost KO mice between the two studies.
Related(20)
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