Ai Feedback
Exact(6)
No significant difference was observed between the dissolution profiles of orifice only on the side of the drug layer and orifices of the same diameter on both sides.
Besides the remarkable enhancement of drug dissolution rate of the granulates in comparison to physical mixtures and pure drug, no significant differences were found between the dissolution profiles of the granulates containing lactose or crospovidone.
The differences between the dissolution profiles of the thermally treated tablets with different excipients were not significant; 100% of the data was not statistically significant (P > 0.05).
The differences between the dissolution profiles of the tablets that contained 60% Avicel and those prepared by using 30% Avicel and 30% lactose were significant (P < 0.05).
A literature review revealed current gaps in the quality assurance of domestic generics in China; specifically, there are significant differences between the dissolution profiles of off-patent originators and domestic generics.
In summary, significant variations were observed between the dissolution profiles of 6 mesalamine formulations examined at a range of pH values, with a few formulations also exhibiting wide tablet-to-tablet variation in the release of 5-ASA.
Similar(54)
The similarity index value was found to be 86.82, which is more than 50 indicateing similarity between the dissolution profile before and after storage.
Similarity of the dissolution profiles between the originator and generic formulations were examined by modified F2 criteria (with specific range for F2 values) or by differences in the average dissolution ratio at particular time points.
The literature review revealed significant differences in the dissolution profiles between originators and generics; therefore, dissolution profiles need to be improved.
Depending on the possible impact of the manufacturing change on the release of the active ingredient and its bioavailability from that formulation, certain manufacturing changes for IR products can be approved solely based on comparability of the dissolution profiles between the post-change and pre-change formulations.
Since the maximum plasma concentrations in vivo were reached between 40 and 60 min and the dissolution profiles of the IR tablets provided little information at later time points, all further dissolution tests with the remaining batches were decided to be run with the same fasted state method but terminated directly after the sampling point at 43 min.
Related(13)
between the etch profiles
between the cam profiles
between the dissolution kinetics
between the dissolution potentials
between the breath profiles
between the user profiles
between the expression profiles
between the dissolution mechanisms
between the dissolution processes
between the protein profiles
between the concentration profiles
between the dissolution characteristics
between the transcript profiles
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com