Sentence examples for been previously implicated to from inspiring English sources

The role of the TRAF family member TRAF6 has been previously implicated to be necessary for full NF-κB activation in response to viral infection and cytosolic RNA [35].

None of the candidate genes identified in this screen have been previously implicated to affect aggressive behavior.

We identified 59 mutations in 57 genes that affect aggressive behavior, none of which had been previously implicated to affect aggression.

Notably transcription factors have been previously implicated to impact activity but also methylation state of CGI (Brandeis et al., 1994; Macleod et al., 1994; Dickson et al., 2010; Lienert et al., 2011).

The presence of a DNA mismatch protein gene has been previously implicated to be involved in modulating recombination events by incorporating or inhibiting the transfer of mobile genetic elements [ 31].

The transcripts DE in response to drought, cold and high-salinity stresses included those associated with aquaporins, dehydrins, membrane-related proteins, senescence-associated proteins, superoxide dismutases, protein kinases, proline oxidase, trehalose phosphatase, phosphate-induced protein, and ubiquitins that have been previously implicated to be responsive to these stresses [ 44- 49].

Callose accumulation was also evaluated (Additional file 1B) as it was previously implicated to have an important role in virus spread [ 17– 17].

The BLAST analysis also revealed that in the three mutants a total of five putative transcription factor genes had been deleted that were previously implicated to be essential genes in F. graminearum.

Furthermore, the expression of several other growth factors and their cognate receptors was examined as these were previously implicated to play a role in the mutual tumor-stroma interplay [ 12, 28, 36].

Both the glutathione and monooxygenase pathways have been previously implicated as core to the responses of many species to a range of chemical stressors [ 13].

TGF-β signaling has been previously implicated in epithelial-to-mesenchymal transition (EMT), as well as maintenance of tumor-initiating cell (TIC) phenotypes [ 81, 82].