Sentence examples for been earlier implicated to from inspiring English sources

Transforming growth factor beta (TGFβ) has been earlier implicated to play a major role in tumor metastases by increasing expression of its downstream genes.

Pemetrexed, which has been earlier implicated in treatment of lung cancer, also exhibited a good binding affinity (− 32.76 .The residues which played a crucial role in the formation of strong H bonds are Ser102, Gly101, Arg243, Lys360, Asn361 and Lys 237.

TbUGP contains all of the crucial amino acids that were earlier implicated in catalysis or SB of UGPs from other eukaryotic species (Chang et al. 1996; Duggleby et al. 1996; McCoy et al. 2007).

Plasticity of early visual areas has generally been implicated to explain perceptual learning that is specific to retinal location or orientation [28].

Exposure to environmental factors (e.g., certain drugs and toxins during early pregnancy) has also been implicated to increase the risk of developing autism in the newborn.

It is noteworthy that PGL has earlier been implicated in optimal mitochondrial functions and maintenance of yeast susceptibility to azole antifungals [36].

The predicted Sp1 site in the Vdac1 gene was of special interest since aberrant Sp1 mediated interaction has earlier been implicated in Huntington's disease mechanism [11].

But the prosecutors said they did not have enough evidence to charge Chechnya's leader, Ramzan A. Kadyrov, who had earlier been implicated in the crime.

Auxin related gene family has earlier been implicated in mediating auxin signaling extensively and controlling almost all the processes from embryogenesis to flowering [17].

Sphingomyelins (SM) and phosphocholines (ceramides) have earlier been implicated with the pathophysiology of OAG [99].

In Alzheimer's disease (which plausibly accounted for most dementia cases in our study), atrophy of the medial temporal lobe (a proxy for limbic system damage implicated in appetite control) and the hippocampal formation are early neuropathological features that might be implicated early on [33], [34].