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Additionally, we plan to investigate whether the blink reflex can be reliably activated by other non-nociceptive vectors, such as fluid droplets applied to the corneal surface, or photic stimuli.
We have studied three commonly used Cre-reporter strains, Z/AP, Z/EG and R26R-EYFP and have demonstrated that although each reporter can be reliably activated by Cre during early development, exposure to Cre in adult hematopoietic cells results in a much lower frequency of marker-positive cells in the Z/AP or Z/EG strains than in the R26R-EYFP strain.
The UPR is mediated via transcriptional responses in both yeast and metazoan cells [ 104, 107], and can be reliably activated by addition of tunicamycin or dithiothreitol (DTT).
Gender differences have been reported suggesting that women engage or recruit additional brain regions such as the frontal lobes, however the parietal region appears to be reliably activated by both genders [ 17, 35, 36].
This region, situated between ventral occipital and temporal lobe, on the border of posterior fusiform and inferior temporal gyrus (ITG) has been shown to be reliably activated by visually presented words [Jobard et al., 2003; Mechelli et al., 2003; Turkeltaub et al., 2002].
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The aMTG was examined as an ROI to explore the aSTS, which was reliably activated by abstract words in the Binder et al. meta-analysis [ 42].
Nevertheless, the fictive behavior evoked by a rise in O2 recapitulated some of the expected response: the backward module (VA neurons) was reliably activated by O2 upsteps from 7% to 21% O2.
The HPA axis is reliably activated by stress exposure, and it is well known that this increases plasma corticosterone levels for up to 6 h after stress exposure [ 14, 23, 26].
PT was reliably activated by many of the pitch stimuli suggesting that a generalized representation of pitch could be formed later in the auditory processing stream than previously considered.
The dorsal part of the human anterior cingulate cortex (dACC) is reliably activated in situations requiring cognitive control, especially during states of conflict.
The insula has also been reliably activated in human pain imaging [ 47].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com