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A new photoacid generator (PAG) is described that can be efficiently activated by two-photon excitation (TPE) and can be used for high-sensitivity three-dimensional micro-patterning of acid-sensitive media.
A protease-mobilized VEGF-C would immediately be available for signaling, whereas pro-VEGF-C could either be activated in the extracellular space or translocate to the endothelial cell surface, where it can be efficiently activated by a CCBE1/protease complex.
Previous studies have shown that the ERK1/2 can be efficiently activated by protein kinase C [47], [48].
The current observations indicate that the Smad1/4 system can be efficiently activated by HBR without the needs of BMP stimulation.
Within the HSC compartments, STAT5 could only be efficiently activated by TPO and high concentrations of IL-3 and GM-CSF.
The CRD of Smo is also important for signaling by Shh, since ΔCRD-Smo cannot be efficiently activated by either Shh or 20(S -OHC but remainS -OHConsive to SAG.
Similar(51)
Liver and muscle glycogen phosphorylases, which are products of distinct genes, are both activated by covalent phosphorylation, but in the unphosphorylated (b) state, only the muscle isozyme is efficiently activated by the allosteric activator AMP.
Nicotinic acetylcholine receptors (nAChRs), a subset of cholinergic receptors, are fast ionotropic receptors and their activation kinetics suggests that they are efficiently activated by these rapid increases in acetylcholine.
TIGAR-hBS2, the more efficient of the two human p53-binding sites, is efficiently activated by either human or mouse p53.
The purified p38α protein was efficiently activated by MKK6 kinase to yield phosphorylated p38α.
Najafov, A., Shpiro, N. & Alessi, D.R. Akt is efficiently activated by PIF-pocket and PtdIns 3,4,5 P3-dependent PtdIns 3,4,5 P3-dependentistance to PDK1 inhibitors.
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