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Lipocalin-type prostaglandin D synthase (L-PGDS), which is responsible for the biosynthesis of prostaglandin (PG) D2, has been found to be present in the atherosclerotic plaque of the human coronary artery and also to be detectable in human serum.
Because of their lipophilic nature, PCBs tend to accumulate in adipose tissues, and therefore could be detectable in human mammary tissues and even in milk.
Together, we found 25 targets that are predicted (by Gene Ontology, UniProt, or the Human Plasma Proteome project) to be detectable in human serum.
Proteomic analysis of genetically engineered mouse models of cancer and isolated cancer cells and cell lines provide alternative methods for identification of potential cancer markers that would be detectable in human blood using sensitive assays.
As mentioned in Background, it has been debated for time about whether translational selection does not exist or is too weak to be detectable in human.
In addition, miR-216a expression was already demonstrated to be detectable in human endothelial cells but not in isolated mouse cardiac myocytes and fibroblasts suggesting that it might take part in the physiological and pathophysiological vascular processes.
Similar(52)
However, other classes of small RNA have also been detected in the extracellular environment: the 3′-end fragments of rRNAs and tRNAs are detectable in human milk [ 26] and U6 snRNA (small nuclear RNA) is up-regulated in the sera of cancer patients [ 27].
We have previously demonstrated using functional magnetic resonance imaging (fMRI) that similar indices of crossmodal facilitation and inhibition are detectable in human cortex when subjects listen to speech while viewing visually congruent and incongruent lip and mouth movements.
Polybrominated diphenyl ethers (PBDEs) have been used as flame retardants in foams, fabrics and plastics, and are common contaminants of household air and dust and bioaccumulate in wildlife, and are detectable in human tissues and in fish and animal food products.
In addition we investigated if protease activities are detectable in human WS.
25HC is detectable in human plasma after ingestion of a meal rich in oxysterols and following a dietary cholesterol challenge.
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