Sentence examples for based on homology using from inspiring English sources

The consensus sequences for each of the clusters were annotated based on homology using BlastX [ 33].

To begin characterizing the differentially expressed genes, we grouped them into functional categories based on homology using Eukaryotic Clusters of Orthologous Groups (KOGs) (Fig.  1d).

The isotigs were annotated based on homology using the BLASTX algorithm [ 25] (threshold values of 1e-10) thethe UniProt sequence database [ 47] and proteins of M. haptotylum [ 20].

Briefly the ESTs (raw sequences) were trimmed of primer and vector sequences, clustered into related groups, based on homology, using the BLASTN algorithm (minimum identity of 81 nucleotides over 90 nucleotides) [ 39], and then assembled and aligned using the CAP3 assembler [ 40].

Methods for the classification of sequencing reads have been based either on homology using sequence similarity or on genomic signatures in terms of oligonucleotide composition.

CFTR constructs were screened for reactivity toward both channel-permeant and channel-impermeant thiol-directed reagents, and patterns of reactivity in TM6 were mapped onto two new, molecular models of the CFTR pore: one based on homology modeling using Sav1866 as the template and a second derived from the first by molecular dynamics simulation.

The sequences were then identified based on homology searches using the web-based nucleotide sequence analysis program MegaBLAST [ 18] from the National Center for Biotechnology Information (NCBI).

Functional assignments were made based on homology searches using blastp [ 59] against protein sequences present in the NCBI nr database and the identification of conserved domains using Pfam [ 60] and InterProScan protein databases [ 61].

First, for an HA of interest, its structure was constructed based on homology modelling using an available HA crystal structure that is highly similar to the target HA (>70% sequence identity).

This would imply that if the folding of the full-length A3G protein does proceed by β2-β2 intheactions, the resulting β-sheet may not be as ordered as was previously predicted based on homology modelling using A2 as a template [12], [16], [35](Figure S1).

Gene candidates and putative activities were identified based on homology searches using t-BLAST [ 28].