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Identification of OA-susceptibility genes would enable us to predict disease phenotypes based on genotype information.
Here, we constructed OA-prediction models based on genotype information from a case-control association study and tested their predictability.
A third set of SNPs was selected to help discriminate individuals from the five geographical regions, based on genotype information.
Results are based on genotype information gathered from 36/37 individuals per population at 59 SNP loci representing 42 genes.
In addition, several breeders had data on Igenity scores produced by Merial (now part of the Neogen Corporation) and based on genotype information for 123 SNP (genotype data).
Recent association studies have uncovered the genetic factors behind OA, its susceptibility genes, which would enable us to predict disease occurrence based on genotype information.
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Therefore, an individualized pain therapy based on genotyping information is not yet imminent.
Based on genotyping information, our method selects an optimized training population, which will be phenotyped after selection.
Isolates that appear to be members of this clone, based on genotyping information, but expressing the nonvaccine serotype 19A have become similarly widespread.
Understanding and predicting the complex interaction between genotype and environment will also be key to select lines based on genotypic information.
Our selection of htSNPs was based primarily on genotype information publicly available from the International HapMap Consortium.
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