at low dose

USAGE SUMMARY

The phrase "at low dose" is correct and usable in written English.
It can be used in contexts related to medicine, pharmacology, or research when discussing the effects or administration of a substance at a lower quantity. Example: "The medication was found to be effective at low dose, minimizing side effects while still providing therapeutic benefits."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

44 human-written examples

At low dose, dissolution of precipitates is dominant, which causes a softening of the material.

Fusion Engineering and Design

Compared with native heparin, 26SCS showed much stronger simultaneous effects on the BMP-2 bioactivity at low dose.

Biomaterials

Carfizomib being a potent protease inhibitor and antineoplastic agent effective against multiple myeloma30 was predicted to have an inhibitory effect even at low dose (1 µM) in HL60 cells despite its reverse agonist response in other cell types and assays.

Nature

Micrographs were recorded at low dose conditions, and at a magnification of 25,000 with typical defocus settings of 5 µm (Fig. 2a, b, Supplementary Fig. 3a c) and 10 µm (Fig. 2c).

Nature

This paper aimed to tackle the macroscopic and microscopic blend uniformity challenges inherently associated with continuous direct compression of cohesive and agglomerated APIs formulated at low dose.

International Journal of Pharmaceutics

We found that administration of OP at low dose (3 μg/kg) enhanced LTM, whereas a dose of 60 μg/kg attenuated it.

Neurobiology of Learning and Memory

Human-verified similar examples from authoritative sources

Similar Expressions

9 human-written examples

Treatment with the iNOS inhibitor aminoguanidine aerosol by inhalation reduced the severity of phosgene-induced ALI when applied at low dose-rates.

Clinical and Translational Medicine

Notably, firm data on the risk of cancer development at low-dose irradiation are needed.

EJNMMI Research

The spectrum of early stage lung cancer presentation at low-dose CT includes solid nodules as well as part-solid nodules and ground-glass nodules (Fig. 1).

Insights into Imaging

This approach increased the power to detect associations between benzene exposure and gene expression, even at low-dose exposure levels.

Environmental Health Perspectives

To assess volumetric measurement variability in pulmonary nodules detected at low-dose chest CT with three reconstruction settings.

European Radiology

Expert writing Tips

Best practice

When using "at low dose" in scientific writing, specify the exact quantity or range to provide clarity and avoid ambiguity. For example, instead of saying "the drug was effective at low dose", specify "the drug was effective at a dose of 5 mg/kg".

Common error

Avoid using "at low dose" without providing context or a specific measurement. Saying a treatment is effective "at low dose" without specifying what constitutes a low dose can be misleading and unhelpful. Always provide the specific dosage or concentration.

Linguistic Context

The phrase "at low dose" primarily functions as an adverbial phrase modifying a verb or adjective to specify the quantity or concentration involved. Ludwig AI confirms its common usage in scientific and medical contexts.

Expression frequency: Very common

Frequent in

Science

95%

Academia

3%

News & Media

2%

Less common in

Formal & Business

0%

Encyclopedias

0%

Social Media

0%

Ludwig's WRAP-UP

The phrase "at low dose" is a common and grammatically correct adverbial phrase used to specify the quantity or concentration of a substance or treatment. Ludwig AI confirms its prevalent use in scientific and medical contexts, where it serves to indicate reduced side effects, minimal impact, or specific experimental conditions. Alternatives include "in small quantities" or "with a low concentration". While generally formal and scientific, specifying the exact quantity is crucial for clarity. Its high frequency in science, academia and news emphasizes its importance in precise communication.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

in small quantities

Emphasizes the limited amount of a substance or agent, rather than specifically focusing on dosage.

in minimal amounts

Highlights the extremely small quantity involved.

with a low concentration

Focuses on the concentration of a substance in a solution or mixture.

at a reduced level

Indicates a decrease from a previously higher level, applicable in various contexts.

in trace amounts

Implies an extremely small and barely detectable quantity.

with limited exposure

Highlights the restricted amount of contact with a substance or influence.

in slight measure

Emphasizes the small degree or extent of something.

at a conservative dose

Specifies that the dose is intentionally kept low to minimize risks.

using a mild dosage

Highlights the gentleness and reduced intensity of the dose.

underdosed

Implies the amount used or prescribed is not enough or not sufficient.

FAQs

How can I use "at low dose" in a sentence?

You can use "at low dose" to describe the administration of a substance in small quantities. For example: "The medication was effective "at low dose", minimizing side effects."

What are some alternatives to saying "at low dose"?

Alternatives include phrases like "in small quantities", "in minimal amounts", or "with a low concentration", depending on the specific context.

Is it better to say "at low dose" or "at a low dosage"?

"At low dose" and "at low dosage" are often interchangeable, but "at low dose" is more concise. "Dosage" typically refers to a prescribed amount, while "dose" can refer to any amount.

What is the significance of using a treatment "at low dose"?

Using a treatment ""at low dose"" often aims to minimize potential side effects or toxicity while still achieving the desired therapeutic effect. It can also be used to study the effects of a substance at levels that mimic environmental exposures.