at a high dose

USAGE SUMMARY

The phrase 'at a high dose' is correct and commonly used in written English.
It is typically used to describe the amount or level of something, often in relation to medication, substances, or treatments. Example: "The doctor prescribed the medication at a high dose, which may cause some side effects."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

It was Haldol at a high dose, and nothing else.

The New York Times - Health

Then he tried a different statin at a high dose, but the cognitive difficulties returned.

The New York Times

Although Effexor did help, it worked best at a high dose, meaning that women also complained of numerous side effects, including constipation, dry mouth and nausea.

The New York Times

Over the study period, 16 patients treated with CVVHD received tigecycline at a high dose.

Intensive Care Medicine Experimental

Toxicity was first tested at a high dose at 7 and 10 days.

Journal of Invertebrate Pathology

When polydimethylsiloxane was irradiated at a high dose in sealed nitrogen atmosphere, carbon element distribution would be changed.

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

However, NDF potential disappearance fraction, NDF total disappearance were increased when the enzyme was added at a high dose.

Livestock Science

We assumed that the initiation of continuous remifentanil infusion at a high dose would prevent adverse events caused by bolus injection and rapidly yield sedative and analgesic effects.

JA Clinical Reports

It neither showed any sign of cytotoxicity nor did it cause any tissue damage in the kidney or elsewhere even when administered at a high dose.

Chemistry Central Journal

administration of morphine at a high dose of 60 nmol into the spinal lumbar space in mice produces a severe hindlimb scratching followed by biting and licking.

Neuropharmacology

Generally, oral or intravenous corticosteroids like methylprednisolone is used at a high dose in the routine therapy for acute attacks which results in a faster recovery from the disability within a duration of three to five days of course [6].

Clinical and Translational Medicine

Expert writing Tips

Best practice

When discussing medication or treatments, specify the exact "at a high dose" to ensure clarity and avoid ambiguity. For example, instead of saying "administered at a high dose", provide the specific dosage amount (e.g., "administered at a dose of 500mg").

Common error

Avoid using "at a high dose" without context. Readers may not understand the implications of the dosage without a reference point. Provide context by comparing it to standard dosages or explaining potential effects.

Linguistic Context

The phrase "at a high dose" functions as an adverbial phrase modifying a verb, adjective, or another adverb. It indicates the quantity or concentration of a substance or treatment being administered. As confirmed by Ludwig AI, it is correct and frequently used.

Expression frequency: Very common

Frequent in

Science

88%

News & Media

11%

Formal & Business

1%

Less common in

Encyclopedias

0%

Wiki

0%

Reference

0%

Ludwig's WRAP-UP

The phrase "at a high dose" is a grammatically sound and commonly used adverbial phrase, predominantly found in science and news media. As confirmed by Ludwig AI, it accurately describes the administration of a substance in significant quantities, often implying a strong effect or potential risks. When using this phrase, clarity is key. Provide context or specify the exact dosage whenever possible to avoid ambiguity. Alternatives such as "in large quantities" or "with a strong concentration" can be used depending on the specific nuance you wish to convey. Understanding the typical contexts and potential implications of "at a high dose" helps ensure its effective and precise use in writing.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

at substantial dosages

More formal way to express the high amount of dosage.

heavily dosed

Implies a significant dosage was administered.

in large quantities

Focuses on the amount rather than a specifically defined dose.

at elevated levels

Refers to higher than normal levels, applicable in various contexts.

with a strong concentration

Emphasizes the strength of the substance used.

given a significant amount

Emphasizes the quantity given, less specific than "dose".

with a high level of exposure

Focuses on the degree of exposure to the substance.

in potent form

Highlights the effectiveness of the substance.

aggressively administered

Highlights the intensity of the administration process.

using maximum strength

Implies using the highest available potency.

FAQs

How can I use "at a high dose" in a sentence?

You can use "at a high dose" to describe the administration of medication, substances, or treatments. For example, "The medication was administered "at a high dose" to quickly alleviate the symptoms."

What are some alternatives to saying "at a high dose"?

Alternatives include phrases like "in large quantities", "with a strong concentration", or "at elevated levels", depending on the context.

Is it always negative to administer something "at a high dose"?

Not necessarily. Administering something "at a high dose" may be necessary for effective treatment, but it can also increase the risk of side effects or toxicity. The context determines whether it's appropriate or detrimental.

Which is more precise, "at a high dose" or specifying the exact dosage?

Specifying the exact dosage (e.g., "500 mg") is more precise than simply saying ""at a high dose"". While ""at a high dose"" implies a significant amount, the precise dosage provides quantifiable information for clarity and accuracy.