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They don't want their music to be as jagged as their emotions; they invite everyone to listen and sing along.
The discarded snowflakes look more like Serras and Duchamps; they're as asymmetrical as Adolph Gottliebs, and as jagged as Clyfford Stills.
Topped with pinnacles as fine as needles, as jagged as saws or as blunt as hammers, these walls of rock overwhelm in their untamed beauty.
While "21 Grams" is as jagged and corrosive as "Sand and Fog" is smooth and somber, it suffers a similar fate: it wants to find tragedy in randomness and disconnection and winds up making its contrivances all the more glaring.
In the ashes, there stood Dikembe Mutombo, an ominous 7-foot-2-inch collection of elbows and knees that are as hard as lug nuts and as jagged as saw teeth.
We needed things that were as jagged as we were.
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He goes on to describe Pattinson's "granite basslines" carrying the melody; Sergeant's guitar playing as "jagged-quartz" and avoiding "anything resembling a solo, apart from the odd flinty peal of lead playing"; de Freitas' drumming as minimal and "surging urgency"; and McCulloch's vocals as having "precocious authority".
Notch, known as a transmembrane receptor that mediates local cell-cell interaction, in mammals, which consists of four distinct subtypes Notch-1, Notch-2, Notch-3, and Notch-4, and nearly all of them are functioned in ligand-dependent manner, the canonical ligands such as delta-like and jagged, as well as other noncanonical ligands like F3/contactin [ 53].
Our data provide the first evidence that Mib1 is essential for Jagged as well as Deltalike ligand-mediated Notch signaling in mammalian development, while Neur1, Neur2, and Mib2 are dispensable.
However, the levels of the ligands, Delta and Jagged as well as the Notch inhibitor, Numb remained unchanged, indicating that TNF mediated repression of Notch-1 is independent of its ligands or inhibitor levels.
So buy yourself a beautiful notebook befitting what will be the start of a sacred journey of healing and scrawl your feelings inside it - as big, jagged and illegible as you like.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com