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During persistent lymphocytic choriomeningitis virus (LCMV) infection, IFNα and IFNβ are highly induced early after infection, and blocking IFN-I receptor (IFNAR) signaling promotes virus clearance.
There are 7 TDC-like enzymes identified in RiceCyc and two of them, encoded by LOC_Os08g04540-TDC1 and LOC_Os08g04560-TDC3 , are highly induced by both abiotic and biotic stresses (Figure 4C).
These matricellular proteins are often needed for ECM remodeling during embryonic development and their expressions are highly induced at sites of injury, inflammation or tumors within the adult organism.
In the Arabidopsis ABF/AREB family, ABF1, ABF2/AREB1, ABF3 and ABF4/AREB2 are highly induced by drought and salt stresses and by ABA in vegetative tissues (Choi et al. 2000; Uno et al. 2000; Fujita et al. 2005; Yoshida et al. 2015).
We suggest that BS location and score information distinguishes between genes that are highly induced versus those that have been poorly induced by ATM.
These results maybe indicated that these genes are highly induced as the major effector genes in the antimicrobial response, while the others play supporting roles.
More specifically, Konstantinopoulos et al. have reported that NRF2, NF-κB, cytokines and proteins involved in inflammatory response pathways are highly induced by carboplatin treatment [19].
p65 GBPs represent well-conserved GTPases in vertebrates, and are highly induced by IFN-γ and less so by IFN-α/β [13].
Three other genes that are highly induced in the presence of metals, mmmQ (Rmet_ 4461), mmtQ (Rmet_4187), and mmsQ (Rmet_4908), encode proteins with apparent signal sequences and similar domains and spacers.
IL-1β and IL-6 however, which are involved in Th17 differentiation [17], are highly induced by CEsHUT in monocytes (Figure 2), suggesting that contact with stimulated T cells might result in a bias towards pro-inflammatory Th17 cells [18].
The data presented here supports the previous finding that etsrp regulates primitive myelopoiesis and vasculogenesis but not erythropoiesis since genes related to the former group are highly induced by etsrp OE while no erythroid genes are induced.
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The phrase "are highly induced " functions as a passive verb phrase , indicating that something is being acted upon to increase or stimulate a particular response. As Ludwig AI states, this phrase describes something that has been strongly influenced or stimulated by a particular factor. The examples illustrate its use in describing gene expression, protein levels, and other measurable quantities.
Expression frequency: Very common
