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Matrix pre-treatment, generally applied as first step of Exploratory Data Analysis EDAA), can alter data structure and thus seriously biasing interpretation [12].
In Japan, combined treatment with proton pump inhibitor (PPI), amoxicillin (AMPC) and CAM have been applied as first line eradication therapy, and MNZ is replaced CAM as second line eradication therapy [18].
In three studies, imatinib (targets c-kit, platelet-derived growth factor [PDGF]) was applied as first- or second-line treatment (300 or 400 mg bid); 2/3 studies showed no responses 31, 62.
TAD chemotherapy, which generally was applied as first induction course, contained 100 mg/m2 cytarabine (days 1, 2 and 3 through 8 every twelve hours), 60 mg/m2 daunorubicin (days 3 5) and 100 mg/m2 6-thioguanine (days 3 9 every twelve hours).
Similar(56)
Methylphenidate is applied as first-line medication, while atomoxetine is preferred in cases where existing comorbidities, like potential drug abuse, are diagnosed.
After washing 3 times with PBS, Alexa 488- and Alexa 594-conjugated goat anti-mouse immunoglobulins (1∶1000; Molecular Probes) were applied as second antibodies at 37°C for 30 min. After three washes with PBS, samples were mounted in mounting medium (Vectashield) and then covered with a cover glass, the images were photographed recorded using a fluorescence microscope (Olympus).
Comparable rates might be achieved even if not applied as first-line therapy.
When ablation has been applied as first-line therapy to patients with resectable disease, the 5-year survival results have been very similar to surgical series [ 30, 61].
Therefore, for patients with ALK-negative ALCL, PBSCT showed unsatisfactory results when it was applied as first-line therapy or salvage therapy.
In the treatment of lung cancer, a number of combination therapy regimens employing platinum compounds have proven to be effective[ 1] and are widely applied as first-line treatment for unresected NSCLC; for example, CDDP + docetaxel, CBDCA + paclitaxel, CDDP + gemcitabine, CDDP + CPT-11, CDDP + paclitaxel, CDDP + vinorelbine, etc[ 2].
The same applies as well to Bruckner's Seventh, Eighth and Ninth Symphonies as opposed to Mahler's last three.
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