an overall disruption

USAGE SUMMARY

The phrase "an overall disruption" is correct and usable in written English.
It can be used to describe a general or comprehensive disturbance or interruption in a system, process, or situation. Example: "The pandemic caused an overall disruption in global supply chains, affecting many industries."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

5 human-written examples

These results suggest that mitochondrial mislocalization in the Aβ42 fly brain is not due to an overall disruption of microtubule-based transport but may be due to an altered transport specific to mitochondria.

Plosone

To test whether Aβ42-induced mitochondrial mislocalization is due to an overall disruption of microtubule-based transport in neurons, we analyzed distributions of tubulin fused to GFP (tub-GFP) and the presynaptic protein synaptotagmin fused to GFP (syt-GFP) in axons and dendrites.

Plosone

In 5T4KO MEF, CXCL12 activation did not lead to ERK1/2 phosphorylation, however this was not due to an overall disruption of the MAPK/ERK pathway as Phorbol 12-Myristate 13-Acetate, (PMA) stimulation led to a MEK but not CXCR4 dependent phosphorylation of ERK1/2 in both genotypes.

Plosone

- Thus, an overall disruption of intracellular membrane compartments would be anticipated.

Communicative and Integrative Biology

Our findings suggest that familial mutations in VPS35 do not lead to an overall disruption of VPS35 protein structure and retromer-dependent protein sorting in neurons, implying that mutations may instead exert subtle or selective effects on specific retromer cargo and/or in specific cell types.

Human Molecular Genetics

Human-verified similar examples from authoritative sources

Similar Expressions

55 human-written examples

Fatigue's strong association with a wide range of patient-reported outcome measures suggests that monitoring fatigue may in itself be a simple way to screen for overall disruption in a patient's life.

Alimentary Pharmacology and Therapeutics

Nevertheless, this analysis suggests that multiple but perhaps interlinked pathways may be affected resulting specifically in a pachytene arrest and overall disruption of spermatogenesis.

Plosone

Fatigue's association with a wide range of patient-reported outcome measures suggests that monitoring fatigue is a simple way to screen for overall disruption in patient life.

Alimentary Pharmacology and Therapeutics

Thus, an overall hydraulic disruption in the mutant genotype might be a signal for stomatal closure.

BMC Plant Biology

"I know that passengers can be frustrated by disruption, but people appreciate that carrying out this work at a time when the railway is less busy reduces overall disruption".

BBC

"This adds significantly to the expense and the overall disruption of the club.

The Guardian - Sport

Expert writing Tips

Best practice

When using "an overall disruption", ensure the context clearly indicates what is being disrupted. Specificity enhances clarity and avoids ambiguity. For instance, instead of just stating "an overall disruption", specify "an overall disruption to the supply chain".

Common error

Avoid using "an overall disruption" when a more precise term would better convey the specific nature of the disturbance. Overusing general terms diminishes the impact of your writing.

Linguistic Context

The phrase "an overall disruption" functions as a noun phrase, typically serving as the subject or object of a sentence. It describes a comprehensive disturbance or interruption. The use of "overall" indicates the disruption affects the entirety of something. Ludwig examples show it describing impacts on processes or systems.

Expression frequency: Rare

Frequent in

Science

67%

News & Media

33%

Formal & Business

0%

Less common in

Academia

0%

Encyclopedias

0%

Wiki

0%

Ludwig's WRAP-UP

The phrase "an overall disruption" is grammatically correct and functions as a noun phrase to describe a comprehensive disturbance. Ludwig AI confirms its usability, noting it's used to describe impacts on processes or systems. While its frequency is relatively rare, the phrase appears in both scientific and news contexts. The primary communicative purpose is to inform about a widespread disturbance. When using this phrase, ensure the context clearly indicates what is being disrupted to avoid vagueness. Related phrases include "a complete breakdown" or "a widespread disturbance", offering alternative ways to express a similar concept.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

a complete breakdown

Changes the adjective to emphasize totality rather than generality.

a total collapse

Replaces "disruption" with a stronger term suggesting complete failure.

a widespread disturbance

Substitutes "overall" with "widespread" to highlight the extent of the disruption.

a general upheaval

Uses "upheaval" to indicate a significant and disruptive change.

a systemic failure

Focuses on the failure of a system rather than a general disruption.

a pervasive interruption

Emphasizes the interruption aspect of the disruption and its widespread nature.

a comprehensive derangement

Employs "derangement" to suggest a state of disorder and disarray.

a sweeping alteration

Highlights the extensive change caused by the disruption.

a thorough disorganization

Replaces "disruption" with "disorganization" to focus on the lack of structure.

a global malfunction

Implies a breakdown in functionality on a large scale.

FAQs

How can I use "an overall disruption" in a sentence?

You can use "an overall disruption" to describe a general disturbance or interruption. For example, "The new regulations caused "an overall disruption" to the market."

What can I say instead of "an overall disruption"?

Alternatives include "a complete breakdown", "a total collapse", or "a widespread disturbance", depending on the specific context.

Which is correct, "an overall disruption" or "a total disruption"?

Both phrases are grammatically correct, but they convey slightly different meanings. "An overall disruption" suggests a general disturbance, while "a total disruption" implies a complete interruption or breakdown.

What's the difference between "an overall disruption" and "a general disturbance"?

"An overall disruption" often implies a more significant and far-reaching impact compared to "a general disturbance". The former suggests a systemic issue, while the latter might refer to a localized or minor incident.