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Moreover, PHYTOZYME BLAST alignment classified the protein as an alcohol dehydrogenase, class V with oxidoreductase activity and zinc ion binding domain.

Finally, some of the pairwise alignments classified as young SDs may in fact not be young, but their high identity may have been maintained by gene conversion [ 6].

Therefore, we performed alignment to classify H3.1, H3.3, and H3-like variants using the established signatures [ 6].

To resolve these, we implemented several post-refinement steps that (i) combine fragments which are separated by a single-nucleotide indel or a mismatch in their alignment; (ii) classify and modify short overlaps in the genome; (iii) fill in short gaps in the transcript between adjacent fragments in the chain; and (iv) find optimal split position for overlapping fragment pairs.

The method exploits information from the reference alignments to classify the sequences in each alignment into a number of subfamilies and to construct a representative model for each protein subfamily, including characteristic conserved blocks and typical start/stop sites.

We first extract 625,890 HS indels from the human chimpanzee macaque mouse multiple alignments and classify them into nonpolymorphic (41%) and polymorphic (59%) indels with reference to the human indel polymorphism data.

The soil types dominant along the proposed highway alignment were classified and characterized in strength.

On the lateral radiograph, stem alignment was classified as neutral, posterior or anterior.

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