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Posterior segment examination on the right showed moderate vitreous inflammation and an advancing edge of necrotizing retinitis associated with scattered intraretinal hemorrhages and retinal vascular telangiectasis (Fig. 1a).

V Y flaps suffer from design problems of the advancing edge, which is usually concave, trying to match another concave edge on the opposite side of the defect.

The flap-in-flap technique uses a second V Y flap at the advancing edge of the main flap to overcome this mismatch, and also improves the amount of advancement possible.

Previous reports have documented the prominent organization of F-actin at the advancing edge of the YSL and EVL during epiboly [24], [32].

This indicates that plaque velocity is established at the advancing edge of an infection wave, and is likely unaffected by cell death in the wake of that wave.

With the enhanced sensitivity of immunofluorescent staining (versus direct imaging of GFP fluorescence, Fig. 2), low levels of ICP0 were detectable in the nuclei of cells at the outermost, advancing edge of HSV-1 plaques ( symbols, Fig. 10A, Fig. S4A).

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Similar(27)

They further indicated that this mechanism probably involved circulation or flow of cytosol through small channels in the actin matrix connecting the bleach zone and advancing edges of the lamella.

Briefly, blocks containing the advancing edges of tumoural and peri-tumoural HCC tissue were used for TMA construction.

After incubation, 5 × 5 mm diameter blocks were cut from the advancing edges of the culture and placed on top of a 2% water agar plates.

In the frozen sections it was noticed that at the advancing edges of the tumour mass, the tumour cells possessed uninhibited guanidinobenzoatase, an enzyme known to degrade the link peptide between cells and fibronectin.

Increased levels of TGF-β1 are observed in many human tumors [ 35- 40, 42, 51, 78- 80], are often localized to the advancing edges of primary tumors and metastases, and are associated with poor clinical outcome [ 39, 41].

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