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Teachers started with the algebra and data strand of the curriculum and continued adding additional strands each year.
Although the simplest example of branched DNA involves only three strands of DNA, complexes involving additional strands and multiple branches are also possible.
These additional strands are not conserved, indicating a more conventional WH-1 domain for most Vps25 proteins.
Interestingly, these additional strands were found to be paired anti-parallel to each other and to the major β-sheet.
This hairpin, together with any additional strands in the insert results in these versions of the fold assuming barrel-like structures with differing degrees of openness.
Besides this symmetric DNA duplex, somewhat weaker signals characterise two additional strands with almost complete assignment (in the following referred to as α strand and β strand), which together form an asymmetric DNA duplex based on interstrand NOEs.
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Both appear to contact partners "side-on" via the edge of the domain on which the additional strand of the 5-stranded versions is situated.
The unifying inserts of this clade typically occur in the region prior to strand 3 and in the region associated with the connector arm or the additional strand of the 5-stranded core.
The C-terminal β-sheet of domain D3 contributes one additional strand to domain D2 completing the 4-stranded β-sheet of the β-sandwich.
But we were in favour of help for first-time buyers as an additional strand in the quest to build a million new homes over the course of this parliament.
One out of every three to four of its intake over the next 12 to 18 months will be a hardware startup, Tandem's Doug Renert tells TechCrunch – injecting an additional strand of physicality to its 'muscle capital' approach.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com