action potential duration

USAGE SUMMARY

The phrase "action potential duration" is correct and usable in written English.
It can be used in contexts related to biology, neuroscience, or physiology when discussing the length of time an action potential lasts in a neuron or muscle cell. Example: "The action potential duration is critical for understanding how signals are transmitted in the nervous system."

✓ Grammatically correct

Science

Academia

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

The potentiation of the Ca transient is accompanied by an increase in the action potential duration.

Cardiovascular Research

As expected, application of IKur blocker produced pronounced action potential duration (APD) prolongation in atrial myocytes.

Stanford University

From experiments, we know that the heterogeneity of action potential duration and morphology is an important mechanism of ventricular tachyarrhythmia.

Stanford University

At the biventricular level, we reduced the apex-to-base and transmural gradients of action potential duration (APD).

Stanford University

Electrophysiological parameters, such as the action potential duration (APD), rates of depolarization and repolarization and beating frequency were assessed.

Journal of Pharmacological and Toxicological Methods

Hondeghem, L. M., Carlsson, L. & Duker, G. Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic.

Nature

Class III antiarrhythmic agents selectively delay the effective refractory period (ERP) and increase the transmembrance action potential duration (APD).

Bioorganic & Medicinal Chemistry Letters

Margolis, E. B., Mitchell, J. M., Ishikawa, J., Hjelmstad, G. O. & Fields, H. L. Midbrain dopamine neurons: projection target determines action potential duration and dopamine D2 receptor inhibition.

Nature

Both azimilide and dofetilide increased monophasic action potential duration, cycle length of idioventricular rhythm, and QT-time.

European Journal of Pharmacology

Monophasic action potential catheters were placed endocardially in both the left and right ventricle to measure action potential duration, visualize early afterdepolarizations, and to assess interventricular dispersion of repolarization (i.e. left ventricular monophasic action potential duration (at 100%) minus right ventricular monophasic action potential duration (at 100%).

European Journal of Pharmacology

The simulated action potential duplicates the experimentally observed effects of changes in [K]o on action potential duration and rest potential.

Yale University

Expert writing Tips

Best practice

When writing about "action potential duration", specify the cell type or tissue (e.g., cardiac myocytes, neurons) for clarity, as the duration varies significantly depending on the context.

Common error

Avoid assuming that a change in "action potential duration" is always indicative of a specific pathological condition without considering other electrophysiological parameters or the influence of experimental conditions.

Linguistic Context

The phrase "action potential duration" primarily functions as a noun phrase. It identifies a specific biophysical property, the duration of an action potential. Ludwig AI confirms the accurate and usable nature of this term, with examples from scientific and academic texts.

Expression frequency: Very common

Frequent in

Science

60%

Academia

40%

Less common in

News & Media

0%

Formal & Business

0%

Encyclopedias

0%

Ludwig's WRAP-UP

In summary, "action potential duration" is a grammatically sound and frequently used noun phrase in scientific and academic writing. Ludwig AI confirms its validity, highlighting its prevalence in describing the temporal characteristics of electrical signaling in cells. It is predominantly found in scientific and academic contexts, with a formal and scientific register. When using this phrase, specifying the cell type or tissue is crucial for clarity. Consider alternatives like "duration of action potential" or "APD restitution" for varied expression. Remember that changes in "action potential duration" should be interpreted cautiously, considering other electrophysiological factors.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

duration of action potential

Rephrases using a prepositional phrase.

action potential length

Uses "length" as a synonym for duration.

cardiac action potential duration

Specifies the context to cardiac function.

transmembrane action potential duration

Emphasizes the transmembrane aspect.

ventricular action potential duration

Narrows down the location to the ventricles of the heart.

atrial action potential duration

Narrows down the location to the atria of the heart.

apd restitution

Focuses specifically on the restitution properties related to action potential duration.

apd dispersion

Focuses on the variability in action potential duration.

action potential repolarization time

Highlights the time it takes for repolarization to occur during action potential.

repolarization time

Highlights the repolarization phase duration instead of the complete action potential.

FAQs

How to use "action potential duration" in a sentence?

You can use "action potential duration" to describe the length of time an electrical signal lasts in a cell, for example: "The drug significantly prolonged the "action potential duration" in cardiac myocytes."

What does "action potential duration" measure?

"Action potential duration" measures the time from the start of depolarization to the completion of repolarization in an excitable cell, reflecting the cell's electrical activity.

What factors affect "action potential duration"?

Several factors can influence "action potential duration", including ion channel activity, membrane potential, temperature, and the presence of pharmacological agents.

What is the clinical significance of changes in "action potential duration"?

Changes in "action potential duration" can be indicative of various cardiac or neurological conditions, such as arrhythmias or channelopathies, and may serve as a target for therapeutic interventions.