a widespread alteration

USAGE SUMMARY

The phrase "a widespread alteration" is correct and usable in written English.
It can be used to describe a significant or extensive change that affects many people or areas. Example: "The recent policy changes resulted in a widespread alteration of the educational curriculum across the country."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

3 human-written examples

Although discolorations, and in particular brown discolorations, represent a widespread alteration, scientific literature on this specific subject is limited.

Heritage Science

Dystrophic neurites, defined as thickened or irregular neuronal processes, are considered to be an expression of a widespread alteration of the neuronal cytoskeleton.

Acta Neuropathologica

A manifestation of genomic shock, which has been experimentally observed in de novo wide hybrids and inferred from the analysis of natural allopolyploids [ 37], is a widespread alteration of DNA sequence in the form of both point mutations and indels [ 38– 40].

BMC Genomics

Human-verified similar examples from authoritative sources

Similar Expressions

57 human-written examples

The results of this study suggest that a more widespread alteration in central pain processing in a subset of IBS patients may be present as they display hypersensitivity to heat, ischemic, and cold pressor stimuli.

PAIN®

We questioned whether aberrant methylation represents a more widespread alteration of the genomic landscape by exploring correlations between the differentially methylated probe sets selected for each tissue type and the much larger sets of variably methylated probes in CpG islands.

Epigenetics and Chromatin

A number of publications have shown widespread alteration in gene expression after treatment of cells in vitro with butyrate, indicating as much as 10% of genes may be affected by butyrate either directly or indirectly.

BMC Cancer

Radiograph and computed tomography scan showed worsening chest abnormalities, with the appearance of a widespread reticulonodular alteration and an opacity in the left middle lobe.

Emerging Infectious Diseases

In its report, the panel said it uncovered new evidence detailing crowd safety deficiencies at the ground, shortcomings in the emergency services response, failures of leadership and co-ordination and widespread alteration of police statements in an attempt to blame the Liverpool fans for what happened.

BBC

The study suggests that plasticity related to spinal nerve injury produces widespread alteration in glutamate transporter function that may contribute to the pathophysiology of neuropathic pain.

Brain Research

Prior to this widespread alteration and loss of primary forest, this region was thought to contain significant orangutan populations [30], [31].

Plosone

Although previous studies have implicated elevated arginase activity and expression in atherogenesis (reviewed in [2], [3], [34]), results of the present investigation demonstrate that an "atherogenic diet" can result in more widespread alterations in arginase activity and arginine metabolism than has previously been recognized.

Plosone

Expert writing Tips

Best practice

When using "a widespread alteration", ensure the context clearly indicates what is being altered and the scope of the alteration. For example, specify the system, process, or area affected by the alteration to provide a comprehensive understanding.

Common error

Avoid using "a widespread alteration" without specifying the context or the specific area that is being altered. Without context, the phrase can be too vague and lack meaningful information for the reader.

Linguistic Context

The phrase "a widespread alteration" functions as a noun phrase. It typically acts as the subject or object of a sentence, describing a significant and extensive change. As Ludwig AI confirms, the phrase is grammatically correct and appropriate for use in written English.

Expression frequency: Uncommon

Frequent in

Science

95%

News & Media

3%

Encyclopedias

2%

Less common in

Formal & Business

0%

Wiki

0%

Social Media

0%

Ludwig's WRAP-UP

In summary, "a widespread alteration" is a grammatically correct and usable phrase in written English, as confirmed by Ludwig AI. It is typically used to describe a significant and broad change affecting many areas, primarily in scientific and formal contexts. While not extremely common, it is an effective way to convey the scope and impact of a particular alteration. When using this phrase, it is important to provide sufficient context to clarify what is being altered and the extent of the alteration. Alternatives like "a broad modification" or "a comprehensive change" may be used depending on the desired emphasis.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

a broad modification

Focuses on the act of modifying something extensively.

a comprehensive change

Highlights the completeness of the change.

an extensive adjustment

Emphasizes the adjustment aspect, suggesting a wide-ranging adaptation.

a sweeping transformation

Implies a dramatic and widespread change.

a general shift

Suggests a change in direction or focus that affects many areas.

a global revision

Highlights a thorough and comprehensive review or update.

a complete overhaul

Indicates a thorough reconstruction or renovation.

a systemic variation

Implies changes affecting an entire system or process.

a ubiquitous modification

Emphasizes the widespread presence of a modification.

an overall adjustment

Suggests a collective adjustment that affects various areas or elements.

FAQs

How can I use "a widespread alteration" in a sentence?

You can use "a widespread alteration" to describe significant changes affecting many areas. For example: "The new regulations caused "a widespread alteration" in the company's operational procedures."

What are some alternatives to "a widespread alteration"?

Alternatives include "a broad modification", "a comprehensive change", or "an extensive adjustment", depending on the specific context.

Is it more appropriate to use "a widespread change" or "a widespread alteration"?

Both phrases are correct, but "a widespread alteration" implies a change that is more structural or fundamental. "A widespread change" is a more general term.

What does "a widespread alteration" typically refer to in scientific contexts?

In scientific contexts, "a widespread alteration" often refers to significant changes in biological processes, genetic structures, or environmental conditions that affect a large population or area.