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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
a very low efficacy
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "a very low efficacy" is correct and usable in written English.
It can be used when discussing the effectiveness or performance of a treatment, intervention, or method in various contexts, such as medicine or research. Example: "The new drug showed a very low efficacy in treating the disease, prompting researchers to reconsider its use."
✓ Grammatically correct
Science
News & Media
Academia
Wiki
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
1 human-written examples
ES cells respond to RA poorly with respect to myogenic differentiation, i.e., RA has a very low efficacy at converting the ES cells into skeletal muscle lineage [ 46].
Science
Human-verified similar examples from authoritative sources
Similar Expressions
59 human-written examples
Because of the very low efficacy of DIM, we considered a TEF model inappropriate for these data.
At 3 microM levels, the MnTDMOE-2-ImP(5+), bearing an oxygen atom within each of the eight side chains, was the most effective and offered much higher protection than MnTE-2-PyP(5+), while MnTDE-2-ImP(5+) was of very low efficacy.
Academia
RNAi by synthetic siRNAs in cardiomyocytes displayed very low efficacy and stability even in vitro, and pharmacological approaches to PLB modulation have failed so far.
Science
In light of the in vivo results provided by the FKN mouse model, we decided to further investigate the involvement of CX3CR1 in breast cancer metastasis by exogenously expressing this receptor in MDA-436 cells, as we found that these cells do not express CX3CR1 and migrate to the bone with very low efficacy.
Science
For example, the knowledge parameter would show a large effect size which would result in a very low sample size whereas, self-efficacy would require a lager sample size.
Science
Considering the supposed preclinically dose-dependent efficacy of irinotecan, a very low dose of irinotecan might lead to negative clinical results.
Science
In essence, this study validated the efficacy of this software as the target glycaemic range was rapidly achieved, with a very low rate of hypoglycaemia.
Science
It was a very low point.
News & Media
Omar kept a very low profile.
News & Media
Cook covered on a very low fire.
News & Media
Expert writing Tips
Best practice
When describing the results of a study or experiment, use "a very low efficacy" to clearly and concisely indicate that the treatment or intervention was not particularly effective. For increased clarity, quantify the efficacy with specific numbers when possible (e.g., "a very low efficacy of less than 10%").
Common error
Avoid confusing "efficacy" with "efficiency". "Efficacy" refers to the ability to produce a desired result, while "efficiency" refers to achieving that result with minimal waste of time, resources or effort. Using "a very low efficiency" implies wastefulness rather than ineffectiveness.
Source & Trust
82%
Authority and reliability
4.5/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "a very low efficacy" functions as a descriptive phrase. It modifies a noun (typically a treatment, method, or intervention) by indicating that its ability to produce a desired result is significantly weak. Ludwig confirms its usability in written English.
Frequent in
Science
45%
News & Media
20%
Academia
15%
Less common in
Wiki
10%
Formal & Business
5%
Reference
5%
Ludwig's WRAP-UP
The phrase "a very low efficacy" is a grammatically sound and widely used expression to describe something's ineffectiveness, as affirmed by Ludwig. It's frequently found in scientific and general contexts, indicating that a treatment, method, or intervention does not produce the desired results. While alternatives like "minimal effectiveness" or "limited efficacy" exist, the choice depends on the specific emphasis you want to convey. A key point is to avoid confusing "efficacy" with "efficiency". When using "a very low efficacy", quantify whenever possible and remember its context. Ludwig's examples underscore its versatility and correctness in various writing scenarios.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
minimal effectiveness
Replaces "efficacy" with "effectiveness" and uses "minimal" to emphasize the low degree.
poor effectiveness
Uses "poor" to describe the level of effectiveness, implying a substandard result.
limited efficacy
Replaces "very low" with "limited", indicating a restricted or reduced effect.
negligible impact
Shifts the focus to "impact" and uses "negligible" to convey an almost non-existent effect.
weak performance
Replaces "efficacy" with "performance" and uses "weak" to denote a low level of capability.
suboptimal result
Focuses on the "result" being less than ideal or expected.
inadequate effect
Uses "inadequate" to describe the "effect", suggesting it is insufficient.
unsatisfactory outcome
Emphasizes the "outcome" being not up to par or meeting expectations.
markedly reduced effectiveness
Adds emphasis to reduced effectiveness, suggesting a notable decline.
significantly impaired efficacy
Highlights that the efficacy is impaired and introduces the element of significance.
FAQs
How can I use "a very low efficacy" in a sentence?
You can use "a very low efficacy" to describe the ineffectiveness of a treatment, drug, or method. For example: "The new vaccine demonstrated "a very low efficacy" in preventing the disease during clinical trials."
What are some alternatives to saying "a very low efficacy"?
Alternatives include phrases like "minimal effectiveness", "poor efficacy", or "limited efficacy", depending on the specific nuance you want to convey.
Is it better to say "low efficacy" or "a very low efficacy"?
"A very low efficacy" emphasizes the degree of ineffectiveness more strongly than simply "low efficacy". The choice depends on how much you want to highlight the lack of effectiveness.
What's the difference between "efficacy" and "effectiveness"?
While often used interchangeably, "efficacy" typically refers to the performance of something under ideal, controlled conditions (like a lab), whereas "effectiveness" refers to its performance in real-world conditions. In many contexts, either term is suitable.
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Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
82%
Authority and reliability
4.5/5
Expert rating
Real-world application tested