Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
a substantial imprint
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "a substantial imprint" is correct and usable in written English.
It can be used to describe a significant or notable mark, influence, or effect left by something or someone. Example: "The artist left a substantial imprint on the local art scene, inspiring many young creators."
✓ Grammatically correct
News & Media
Science
Encyclopedias
Wiki
Alternative expressions(15)
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
1 human-written examples
That makes for a substantial imprint.
News & Media
Human-verified similar examples from authoritative sources
Similar Expressions
59 human-written examples
We noticed that a substantial number of imprinted genes displaying weak to moderate parental bias localize to the vicinity of imprinted genes showing stronger parental bias.
Science
Based on recent predictions, the number of mammalian imprinted genes may range between 100 and 600 genes [ 1- 4], i.e. a substantial number of imprinted genes are already identified.
Science
Although expression differences between parental alleles are commonly assumed to be all-to-none, a substantial number of imprinted genes have been shown to exhibit a biased expression from one of the parental alleles in at least some tissues (Dao et al., 1998; Lewis et al., 2004; Khatib, 2007; Babak et al., 2008; Menheniott et al., 2008; Tierling et al., 2009; Gregg et al., 2010; Gregg, 2014).
Science
These two strong factors imprint a substantial cultural and conceptual unity upon all these housing types.
Such definition, however, is incomplete since a substantial number of known imprinted genes appear preferentially expressed from one of the parental alleles.
Science
Dr. Dulac said that she expects a substantial, though lesser, proportion to be imprinted in people — maybe some 1 percent of the genome — because humans are more monogamous than mice and so the parents' interests are more closely aligned.
News & Media
By this analysis, about half of the genome is differentially methylated between sperm and oocyte, so the potential for imprinting extends over a substantial fraction of the genome.
Science
Given that only 0.6% of all high-coverage sites were within 10 kb of a known imprinted locus, this is a substantial (29.3-fold), and highly significant enrichment of ASHM sites around imprinted regions (P < 2.2 × 10−16, χ² test).
Science
Examination of the expression of imprinted genes have shown that nearly all human ES cell lines possess a substantial degree of stability in terms of genomic imprinting status [30].
Science
Importantly, most of the newly identified imprinted genes, as well as a substantial number of those previously known, display weak-to-moderate parental biases rather than the more conventionally expected monoallelic expression.
Science
Expert writing Tips
Best practice
Use "a substantial imprint" to convey that something has left a significant and lasting effect. It is more formal than 'a big impact' and suitable for academic or professional writing.
Common error
Avoid using "a substantial imprint" in casual conversations or informal writing. Opt for simpler phrases like 'a big effect' or 'a major impact' in those situations.
Source & Trust
84%
Authority and reliability
4.5/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "a substantial imprint" functions as a noun phrase, where "substantial" is an adjective modifying the noun "imprint". According to Ludwig AI, this phrase is usable in written English, and it is used to describe a significant or notable mark, influence, or effect.
Frequent in
News & Media
26%
Science
25%
Wiki
10%
Less common in
Encyclopedias
2%
Formal & Business
1%
Reference
0%
Ludwig's WRAP-UP
In summary, the phrase "a substantial imprint" denotes a significant and lasting effect or influence. As confirmed by Ludwig AI, this grammatically sound phrase is best suited for neutral to formal contexts, such as academic papers, news articles, and professional communications. While its usage isn't exceptionally frequent, it effectively conveys the notion of an enduring impact. Alternatives like "a considerable influence" or "a significant effect" can be used depending on the nuances of the context.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
a considerable influence
Replaces 'imprint' with 'influence', focusing on the power to affect someone or something.
a significant effect
Substitutes 'imprint' with 'effect', highlighting the result or consequence of an action.
a marked impact
Uses 'impact' instead of 'imprint', suggesting a forceful or considerable effect.
a notable impression
Replaces 'imprint' with 'impression', focusing on the effect on someone's mind or feelings.
a profound effect
Emphasizes the depth and intensity of the effect.
a lasting legacy
Highlights the enduring nature of the impact.
a major contribution
Focuses on the act of giving or providing something significant.
a tangible result
Emphasizes the concrete and perceptible outcome.
an important mark
Uses 'mark' instead of 'imprint', suggesting a noticeable trace or indication.
a dominant influence
Highlights the prevailing power in shaping something.
FAQs
How can I use "a substantial imprint" in a sentence?
You can use "a substantial imprint" to describe a significant and lasting effect or influence. For example, "The artist left "a substantial imprint" on the local art scene" or "His policies had "a substantial imprint" on the company's culture".
What are some alternatives to "a substantial imprint"?
Alternatives to "a substantial imprint" include phrases like "a considerable influence", "a significant effect", or "a marked impact", depending on the specific context.
What does "a substantial imprint" mean?
"A substantial imprint" refers to a significant and lasting effect or influence left by someone or something. It suggests that the impact is considerable and noticeable.
Is "a substantial imprint" formal or informal?
"A substantial imprint" is generally considered a more formal phrase. In informal contexts, you might prefer alternatives like "a big impact" or "a major effect".
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
84%
Authority and reliability
4.5/5
Expert rating
Real-world application tested