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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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a substantial enlargement

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "a substantial enlargement" is correct and usable in written English.
It can be used when discussing an increase in size, scope, or extent, often in contexts such as business, architecture, or policy changes. Example: "The company announced a substantial enlargement of its manufacturing facilities to meet growing demand."

✓ Grammatically correct

Science

News & Media

Formal & Business

Human-verified examples from authoritative sources

Exact Expressions

3 human-written examples

During necropsy, a substantial enlargement of the spleen was observed in male Plg −/− and MMP9 −/−:Plg −/− mice and female MMP9 −/−:Plg −/− mice with increasing age of the animals.

In this study on age-related changes of PPS, we additionally confirmed previous findings about a substantial enlargement of RFs in the hindpaw representation in aged rats (Spengler et al. 1995; Godde et al. 2002; David-Jurgens et al. 2008).

Our electron microscopical analysis revealed that in yeast cells grown under CR on 0.2% glucose and recovered upon entry into a quiescent state on day 7 of cell culturing, LCA (i) causes a substantial enlargement of mitochondria; and (ii) significantly reduces the number of these organelles.

Science

Aging

Human-verified similar examples from authoritative sources

Similar Expressions

56 human-written examples

The case for expanding the territory of Gaza is indeed not difficult to make, even though one particularly interesting proposal that envisages a more substantial enlargement would also require Egyptian participation in a land swap.

For me it is clear that, without strong foundations, the Union will not come through a further substantial enlargement unscathed.

The first published description of a case of leukemia in medical literature dates to 1827, when French physician Alfred-Armand-Louis-Marie Alfred-Armand-Louis-Marie Alfred-Armand-Louis-Marie Alfred-Armand-Louis-Marie Velpeauer, weakness, urinary stones, andescribedtial enlargement of the liver and spleen.

The proposed synthesis resulted in microporous carbon spheres having the surface area of 2130 m2 g−1, total pore volume of 1.10 cm3 g−1, and the micropore volume of 0.78 cm3 g−1, and led to the substantial enlargement of microporosity in these spheres, especially in relation to fine micropores (pores below 1 nm), which enhance CO2 adsorption.

Science

Carbon

MAP infection in unvaccinated mice caused substantial enlargement of the spleen.

Science

Plosone

Coronal sections showed substantial enlargement of internal cerebral veins that drain the caudate/putamen bilaterally.

It is likely that the substantial enlargement of mitochondria and the resulting expansion of both mitochondrial membranes observed in yeast cultured with exogenously added LCA were due to the age-related increase in the glycerophospholipid/protein ratio (and, thus, in glycerophospholipid abundance) of mitochondrial membranes seen in these cells.

Science

Aging

In the present study, we confirmed that relevant pulmonary hypertension may be missed by the miniaturized system (Table 1), especially in the absence of significant right ventricular enlargement as observed in a substantial proportion of acute cor pulmonales [ 17].

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Expert writing Tips

Best practice

When using "a substantial enlargement", ensure the context clearly defines what is being enlarged to avoid ambiguity. For instance, specify "a substantial enlargement of the research budget" rather than just "a substantial enlargement."

Common error

Avoid using "a substantial enlargement" repeatedly within the same document. Vary your language by using synonyms like "significant expansion" or "considerable increase" to maintain reader engagement and prevent monotony.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

82%

Authority and reliability

4.3/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "a substantial enlargement" functions as a noun phrase, where "substantial" modifies the noun "enlargement". It describes the degree or extent of the increase in size, scope, or quantity. Ludwig AI showcases its use in varied contexts, such as describing the enlargement of a spleen or cerebral veins.

Expression frequency: Uncommon

Frequent in

Science

34%

News & Media

33%

Formal & Business

11%

Less common in

Encyclopedias

7%

Wiki

7%

Reference

7%

Ludwig's WRAP-UP

In summary, "a substantial enlargement" is a grammatically correct and usable phrase that denotes a significant increase in size, scope, or extent. Ludwig AI confirms this, as the phrase appears in varied contexts from scientific research to news reports. While synonyms like "significant expansion" or "considerable increase" may be used for variety, "a substantial enlargement" effectively conveys a noteworthy increase. While not as common as some alternatives, it remains a useful phrase in formal and neutral registers, requiring careful contextualization to avoid ambiguity.

FAQs

How can I use "a substantial enlargement" in a sentence?

You can use "a substantial enlargement" to describe a significant increase in size, scope, or extent. For example, "The company announced "a substantial enlargement" of its facilities."

What are some alternatives to "a substantial enlargement"?

Alternatives include "a significant expansion", "a considerable increase", or "a major growth" depending on the specific context.

Is it better to say "substantial enlargement" or "significant enlargement"?

Both "substantial enlargement" and "significant enlargement" are grammatically correct. The choice depends on the nuance you want to convey. "Substantial" implies a considerable size, while "significant" emphasizes the importance or impact of the enlargement.

Can "a substantial enlargement" refer to abstract concepts?

Yes, "a substantial enlargement" can refer to abstract concepts such as a budget, influence, or market share, not just physical objects. For example, "There has been "a substantial enlargement" of their market share over the past year."

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Source & Trust

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Authority and reliability

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Expert rating

Real-world application tested

Most frequent sentences: