a stringent alignment

USAGE SUMMARY

The phrase "a stringent alignment" is correct and usable in written English.
It can be used when referring to a strict or precise agreement or arrangement, often in contexts like project management, research, or policy implementation. Example: "The team emphasized the need for a stringent alignment of their objectives to ensure project success."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

3 human-written examples

In the first step, a stringent alignment is performed to efficiently retrieve Illumina short reads and their complementary sequences, called seed- reads.

BMC Genomics

Then individual SNPs may be genotyped by performing a stringent alignment of the sequencing reads against the reference genome, allowing for all the putative variable positions.

Bioinformatics

The first, "stringent" phase reports reads with near-perfect matches to the reference genome by using long and sparse seed substrings (seed length of 0.5 times the average read length, constrained to a minimum of 9 and a maximum of 31; seed spacing equal to 1 plus 0.25 times the square root of the read length, rounded down) and a stringent alignment score threshold (0.9 times the read length).

BMC Genomics

Human-verified similar examples from authoritative sources

Similar Expressions

57 human-written examples

In order to evaluate the most expressed ESTs, a less stringent alignment using a shared identity of > 65 out of 100 nucleotides was used.

BMC Genomics

Because of the smaller genome size of viruses, we used a more stringent alignment strategy (i.e., 100% identity and ≥1% coverage), and 3 most abundant viral species were identified.

Environmental Science & Technology

For each pair (A i, B i) of query domain instances that meets the stringent alignment threshold to a template interacting domain instance pair (A, B), we infer the interaction interface residues in (A i, B i) as the residues that are aligned to the interaction interface residues in (A, B).

BMC Systems Biology

A second strategy was to separately align the At and Dt genome reads from two varieties using very stringent alignment parameters or a precharacterized genome-specific SNP index to separate short reads into their subgenome of origin before varietal SNP identification (Byers et al. 2012; Salmon et al. 2012; Page et al. 2013a, b).

G3: Genes, Genomes, Genetics

The stringent alignment (Alignment 3) revealed a robust phylogenetic position (ML 99% bootstrap, BP 100% posterior probability and NJ 100% bootstrap) of the brain genotype as a sister group to the monophyletic clade of liver, Brazil-1 and Brazil-2 genotypes, together with M. melleni.

Plosone

An additional more stringent alignment was constructed by removing ambiguously aligned sites using Gblocks [ 69] as well as visual examination.

BMC Genomics

From the total of 52,157 SNPs called by the cluster file to be polymorphic in the diversity panel, a stringent BLAST alignment (zero mismatches) of their flanking sequences to the draft B. napus reference genome identified 10,065 SNPs with potentially two or more loci in the B. napus genome, along with 6,930 SNPs showing no identical BLAST hit.

BMC Genomics

CQ-calculate uses stringent alignment criteria requiring the entire read to align with zero mismatches.

BMC Genomics

Expert writing Tips

Best practice

When describing processes requiring high accuracy, use "a stringent alignment" to emphasize the need for precision and minimal deviation.

Common error

Avoid using "a stringent alignment" when a simple or approximate alignment is sufficient. Overstating the required precision can lead to unnecessary complexity and wasted resources.

Linguistic Context

The phrase "a stringent alignment" functions as a noun phrase, where "stringent" modifies the noun "alignment". Ludwig AI indicates its correctness in written English, typically appearing within scientific and technical documents.

Expression frequency: Rare

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Ludwig's WRAP-UP

In summary, "a stringent alignment" is a noun phrase used to convey the need for a precise and accurate arrangement, primarily within scientific and technical fields. Ludwig AI confirms that this phrase is correct and commonly used in scientific writing, with applications often revolving around data analysis, genome sequencing, and experimental procedures. While grammatically sound, its frequency is rare and best suited for formal contexts where precision is key.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

a rigorous matching

Replaces 'alignment' with 'matching' emphasizing the act of finding a correspondence.

a strict correspondence

Uses 'correspondence' instead of 'alignment', highlighting the matching aspect.

a precise configuration

Substitutes 'alignment' with 'configuration' indicating a specific arrangement.

an exacting arrangement

Replaces 'stringent' with 'exacting' emphasizing the demanding nature of the arrangement.

a demanding fit

Uses 'fit' instead of 'alignment', focusing on the degree of conformity required.

a close agreement

Emphasizes the harmony or accord between elements.

a tight juxtaposition

Highlights the close proximity and arrangement of elements.

a meticulous positioning

Focuses on the careful and precise placement of elements.

an accurate mapping

Replaces 'alignment' with 'mapping' suggesting a correspondence between different sets of data.

a faithful representation

Emphasizes the accuracy and reliability of the alignment.

FAQs

How can I use "a stringent alignment" in a sentence?

You can use "a stringent alignment" to describe processes requiring high accuracy, such as: "The experiment required "a stringent alignment" of the laser beam to achieve optimal results."

What can I say instead of "a stringent alignment"?

You can use alternatives like "a rigorous matching", "a strict correspondence", or "a precise configuration" depending on the context.

Which is correct, "a stringent alignment" or "a loose alignment"?

Both phrases are grammatically correct, but they describe opposite levels of precision. "A stringent alignment" implies a high degree of accuracy, while "a loose alignment" suggests a more approximate fit.

What's the difference between "a stringent alignment" and "a rough alignment"?

"A stringent alignment" indicates a precise and carefully controlled arrangement, whereas "a rough alignment" implies an approximate or preliminary arrangement, often done quickly or without precise tools.