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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
a significant dose of
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "a significant dose of" is correct and usable in written English.
It can be used to describe a considerable amount of something, often in a metaphorical sense, such as emotions, experiences, or substances. Example: "The presentation included a significant dose of humor, which kept the audience engaged throughout."
✓ Grammatically correct
News & Media
Science
Alternative expressions(20)
a considerable amount of
a substantial measure of
a large quantity of
a substantial amount of
a considerable quantity of
a notable degree of
a marked increase in
an appreciable level of
a good deal of
a generous helping of
an ample supply of
a considerable dose of
a tremendous dose of
a substantial dose of
a large dose of
a strong dose of
a significant part of
a bitter dose of
a disruptive dose of
a daily dose of
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
22 human-written examples
But it subjected him to a significant dose of radiation.
News & Media
But it came with a significant dose of partisan politics.
News & Media
Northern Ireland, with their steely home form, are entitled to a significant dose of quiet optimism.
News & Media
Dr. McGill acknowledges that showing cellular processes can involve a significant dose of conjecture.
News & Media
But when they do, the first fly balls there will carry with them a significant dose of intrigue.
News & Media
Younger teenagers might not have seen 2002's Spider-Man; let's just say they're going to experience a significant dose of superhero deja vu when it next comes on the telly.
News & Media
Human-verified similar examples from authoritative sources
Similar Expressions
38 human-written examples
Condition cannot be explained by a significant dose increase of olanzapine LAI, initiation or addition of oral olanzapine or other sedating medication, or new exposure to olanzapine LAI.
Science
However, many clinical trials with O-BG or PaTrin-2 have observed an increase in toxicity or adverse events, resulting in a significant dose reduction of TMZ.
Science
We did not find a significant dose effect of ApoE4 on hippocampal loss rates in contrast to another study (van de Pol et al., 2007).
Science
The hydro alcoholic extract of Cytisus scoparius exhibited a significant dose dependent inhibition of DPPH activity, with a 50% inhibition (IC50) at a concentration of 1.5 μg/ml.
All cell lines showed a significant dose dependent inhibition of proliferation starting at a concentration of 0.5 μM PDA-66.
Science
Expert writing Tips
Best practice
When using "a significant dose of", consider the connotations of "dose". It can sometimes imply something medicinal or even slightly negative, such as "a significant dose of radiation". Choose this phrase when you want to convey a strong impact or effect.
Common error
Avoid using "a significant dose of" too frequently in contexts where the idea of a "dose" is inappropriate or misleading. Overuse can dilute the impact and make your writing sound unnatural. Consider alternatives like "a substantial amount of" or "a considerable degree of" when the "dose" metaphor doesn't quite fit.
Source & Trust
89%
Authority and reliability
4.5/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "a significant dose of" functions as a modifier describing the quantity or extent of something. It often introduces a noun, indicating that something is present in a notable or considerable amount, and is deemed correct by Ludwig.
Frequent in
News & Media
57%
Science
43%
Formal & Business
0%
Less common in
Academia
0%
Encyclopedias
0%
Wiki
0%
Ludwig's WRAP-UP
In summary, "a significant dose of" is a grammatically sound phrase used to emphasize the notable amount or degree of something. As Ludwig AI indicates, its primary function is to modify a noun, highlighting the magnitude or impact of a particular element. Appearing most frequently in "News & Media" and "Science" contexts, its register is generally neutral, fitting for both formal and informal communication while tilting slightly towards formality. When choosing this phrase, be mindful of the connotations of "dose" and ensure it aligns with the intended meaning. Alternatives like "a considerable amount of" or "a substantial measure of" can be used when a more neutral or precise expression is needed.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
a considerable amount of
Emphasizes the quantity or extent of something more directly.
a substantial measure of
Suggests a notable quantity or degree, often in a more formal context.
a large quantity of
Focuses on the amount of something, potentially tangible.
a notable degree of
Highlights the extent to which something is present, often referring to abstract qualities.
a marked increase in
Implies a clear and noticeable rise or addition.
an appreciable level of
Indicates a quantity or degree that is easily perceived or recognized.
a good deal of
Informal way to express a large quantity or amount.
a generous helping of
Suggests an abundant or ample portion of something, often used metaphorically.
an ample supply of
Focuses on availability and abundance.
a healthy portion of
Conveys a substantial and beneficial amount.
FAQs
How can I use "a significant dose of" in a sentence?
You can use "a significant dose of" to describe a considerable amount or degree of something, often in a metaphorical sense. For example, "The movie provided "a significant dose of" suspense" or "The project required "a significant dose of" patience".
What are some alternatives to "a significant dose of"?
Alternatives include "a considerable amount of", "a substantial measure of", or "a large quantity of", depending on the specific context.
Is "a significant dose of" formal or informal?
"A significant dose of" is generally considered neutral in tone and can be used in both formal and informal contexts, although it leans slightly towards the formal side. Consider your audience and purpose when deciding whether to use it.
When is it not appropriate to use "a significant dose of"?
Avoid using "a significant dose of" when referring to things that are not typically measured in doses, or when the term "dose" introduces an unwanted medical or negative connotation. In these cases, opt for a more neutral alternative like "a substantial amount of" or "a considerable quantity of".
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Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
89%
Authority and reliability
4.5/5
Expert rating
Real-world application tested