a significant blockage

USAGE SUMMARY

The phrase "a significant blockage" is correct and usable in written English.
It can be used to describe a major obstruction or hindrance in various contexts, such as medical, logistical, or metaphorical situations. Example: "The construction work has caused a significant blockage on the main road, leading to heavy traffic delays."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

6 human-written examples

A coroner's report said that Herrion's death was caused by heart disease that left a significant blockage in his right coronary artery. 1 2 Next Page » Rob Reischel contributed reporting from Green Bay, Wis.

The New York Times - Sports

Results demonstrated a significant blockage of VEGF VEGFR binding by bevacizumab.

Analytical Chemistry

The results demonstrated a significant blockage of VEGF VEGFR binding by bevacizumab.

Analytical Chemistry

This apoptosis may be in part mediated by a significant blockage in G0/G1 phase.

BioMed Research International

There was also a significant blockage of its uptake in several integrin αvβ3-positive normal organs by coinjection of excess RGD2.

Bioconjugate Chemistry

Comparatively, the effect was milder after cyclin B1 inhibition, yet a significant blockage of the cells in G2/M phase was still present.

BMC Cancer

Human-verified similar examples from authoritative sources

Similar Expressions

54 human-written examples

The angiogram showed significant blockage in a number of coronary arteries, normal heart function and no heart attack.

The New York Times

"This shortfall, due to recent uncertainty, has created a significant noticeable blockage in projected revenue streams for the club.

BBC

Significant blockage from such inflammation and scarring generally occurs within about three months after the placement of a stent.

The New York Times

Mass deposition was minimal down to 532 µm; however, for smaller grid apertures, significant blockage was observed at all airflow rates (60 140 L·min−1).

Journal of Pharmaceutical Sciences

In contrast ceftazidime (Fig. 1d) and ampicillin (Fig. 1e) caused no significant blockage of the ionic current indicating negligible interaction with the channel.

Plosone

Expert writing Tips

Best practice

When describing abstract concepts like progress or communication, use "a significant blockage" to denote a serious impediment to flow or understanding. For example: "Lack of funding created "a significant blockage" in the project's development."

Common error

Avoid using "a significant blockage" in casual conversation or informal writing. Simpler terms like 'problem' or 'obstacle' may be more appropriate for a less formal tone.

Linguistic Context

The phrase "a significant blockage" functions as a noun phrase, where 'significant' acts as an adjective modifying 'blockage'. Ludwig AI indicates that this is a correct and usable phrase in written English.

Expression frequency: Uncommon

Frequent in

Science

60%

News & Media

40%

Formal & Business

0%

Less common in

Wiki

0%

Encyclopedias

0%

Reference

0%

Ludwig's WRAP-UP

The phrase "a significant blockage" is grammatically correct and usable in English. As Ludwig AI confirms, it effectively describes a notable obstruction or impediment. While applicable across various domains, its use is most frequent in scientific and news contexts. Remember to tailor your word choice to the formality of the situation; simpler alternatives may be better suited for informal communication. By understanding its nuances, you can confidently use "a significant blockage" to convey impactful obstructions in your writing.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

a significant obstruction

Repeats the root of the query, focusing on the object being blocked.

a major obstruction

Emphasizes the size or importance of the blockage.

a considerable impediment

Highlights the hindering effect of the blockage.

a substantial obstruction

Similar to 'major obstruction' but with a slightly different nuance.

a notable hindrance

Focuses on the noticeable aspect of the blockage's effect.

a major impediment

Synonymous with 'major obstruction' and 'considerable impediment'.

a marked impediment

Indicates a clear and obvious blockage.

a serious obstruction

Conveys the severity of the blockage.

a critical obstruction

Highlights that the blockage is crucial or vital.

a severe hindrance

Indicates the blockage is particularly harsh or difficult.

FAQs

How can I use "a significant blockage" in a sentence?

You can use "a significant blockage" to describe a major obstruction or hindrance. For instance, "The accident caused "a significant blockage" on the highway" or "There's "a significant blockage" in communication between departments".

What are some alternatives to "a significant blockage"?

Alternatives include "a major obstruction", "a considerable impediment", or "a substantial obstruction". The best choice depends on the specific context.

When is it appropriate to use "a significant blockage"?

It's appropriate when you want to emphasize the importance or size of an obstruction. It works well in both formal and technical contexts, where precision is important. Consider using simpler terms in more casual contexts.

Is "a significant blockage" formal or informal?

The phrase "a significant blockage" is relatively formal and is suitable for academic, professional, or news contexts. In informal settings, simpler synonyms might be preferable.