Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
a significant alteration
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "a significant alteration" is correct and usable in written English.
It can be used when discussing a notable or important change in a situation, document, or object. Example: "The report highlighted a significant alteration in the company's financial strategy that could impact future growth."
✓ Grammatically correct
Science
News & Media
Wiki
Formal & Business
Encyclopedias
Alternative expressions(20)
a marked transformation
a drastic shift
a major adjustment
a material transformation
a fundamental restructuring
a sweeping reform
a fundamental realignment
a significant shift
a material change
a substantial adjustment
a considerable modification
a material shift
a material reorientation
a gradual change
a sea change
a substantial change
a material changes
a major change
a radical departure
a major modification
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
60 human-written examples
Elongation stage (6 DPA) fibers from Li 1 demonstrated a significant alteration in transcript profiles, with 1,398 target sequences showing altered expression in the mutant.
Science
He has worked with the pitching coach, Mel Stottlemyre, apparently making a significant alteration to his delivery to keep him from telegraphing his pitches.
News & Media
However the assessors preferred brick, a significant alteration that allowed for Nordic boldness and dexterous external craftsmanship, which was revealed after the recent refurbishment.
News & Media
These changes are all well and good, but the most exciting part of the WTA map — for the casual fan — is a significant alteration of a ranking system that can only be described as byzantine.
News & Media
The reasoning behind this was that such a significant alteration in social attitudes can be effective only if instituted at the earliest possible age, when the child's nature is pliant and unformed.
News & Media
Towards the 1960s, Apel claims, the Heideggerian conception of truth undergoes a significant alteration.
Science
A significant alteration in the texture and morphology was also observed for the modified CN samples.
Direct compression did not induce a significant alteration in the starch-hydrolysing activity.
However, in this study AST elevation was followed by a significant alteration in AST/ALT ratio (Figure 2A).
Science
Presumably, a significant alteration in the backbone dynamics makes the difference between SVMPs that induce hemorrhage and the inactive ones.
Science
A significant alteration in more than 30 microRNAs (~8% of the assays) was detected during the screening.
Expert writing Tips
Best practice
When using "a significant alteration", ensure the context clearly indicates what is being altered and the impact of that alteration. For example, specify "a significant alteration in policy" rather than just "a significant alteration."
Common error
Avoid using "a significant alteration" for minor changes. Reserve it for changes that genuinely have a substantial impact or effect. Using it for trivial adjustments weakens its meaning and can mislead your audience.
Source & Trust
83%
Authority and reliability
4.5/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "a significant alteration" functions as a noun phrase, with "significant" acting as an adjective modifying the noun "alteration". Ludwig AI confirms its grammatical correctness and usability.
Frequent in
Science
65%
News & Media
25%
Wiki
5%
Less common in
Formal & Business
3%
Encyclopedias
1%
Reference
1%
Ludwig's WRAP-UP
In summary, "a significant alteration" is a grammatically correct and frequently used phrase to describe a notable change. As confirmed by Ludwig, it is common across various contexts, especially in scientific and news domains. When using this phrase, ensure that the alteration is indeed significant and the context clarifies what has been altered and its impact. Consider alternatives like "a major modification" or "a considerable change" depending on the specific nuance you wish to convey.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
a major modification
Emphasizes the scale and impact of the change.
a substantial adjustment
Focuses on the act of making something fit or conform.
a considerable change
Highlights the degree or extent of the difference.
a marked transformation
Suggests a visible or noticeable change in form or appearance.
a profound revision
Implies a deep and thorough alteration.
a sweeping reform
Denotes a widespread and comprehensive change.
a drastic shift
Highlights a sudden and extreme change in direction or position.
a fundamental restructuring
Emphasizes an alteration to the basic structure or organization.
a notable deviation
Focuses on a departure from a standard or expected course.
a radical departure
Highlights a complete divergence from previous norms or practices.
FAQs
How can I use "a significant alteration" in a sentence?
You can use "a significant alteration" to describe an important change. For example, "The new regulations represent "a significant alteration" in environmental policy."
What phrases can I use instead of "a significant alteration"?
Alternatives to "a significant alteration" include "a major modification", "a substantial adjustment", or "a considerable change" depending on the context.
Is it better to say "significant change" or "a significant alteration"?
Both "significant change" and "a significant alteration" are grammatically correct. "A significant alteration" is more formal and emphasizes the act of changing something, while "significant change" is a more general term.
What's the difference between "a significant alteration" and "a slight modification"?
"A significant alteration" describes a major change with noticeable impact, whereas "a slight modification" refers to a minor adjustment that may not be immediately apparent. The choice depends on the degree of change you wish to convey.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
83%
Authority and reliability
4.5/5
Expert rating
Real-world application tested