a reduced efficacy of

USAGE SUMMARY

The phrase "a reduced efficacy of" is correct and usable in written English.
It can be used in contexts where you want to describe a decrease in effectiveness or performance of something, such as a treatment, process, or product. Example: "The study found a reduced efficacy of the vaccine against the new variant of the virus."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

23 human-written examples

The understandable need to treat all the migraine attacks combined with a reduced efficacy of rescue medications, can determinate the occurrence of medication overuse [7].

The Journal of Headache and Pain

Here, we have described a reduced efficacy of ITNs in older children for febrile episodes.

Plosone

As the efficacy of selection is proportional to the product of the selective coefficient and the effective population size [4], the relatively small effective population size of island species should result in a reduced efficacy of natural selection.

Plosone

Conversely, a reduced efficacy of HIF-1-inhibitors might be anticipated for treatment of p53 defective tumors, an aspect that may constitute a confounding factor in clinical trials of HIF-1α-inhibiting treatment regimes.

Plosone

As observed with respect to the increase in flexibility in the catalytic function of psychropilic enzymes, a reduced efficacy of the hydrophobic interactions [61] may have a functional advantage, whereas in the case of short IDP binding motifs it may curtail the functional advantages they provide in mesophiles.

Plosone

Advanced age has been associated with a reduced efficacy of ischemic preconditioning to protect against ischemic cell death [ 9].

Cardiovascular Diabetology

Human-verified similar examples from authoritative sources

Similar Expressions

37 human-written examples

Figure 3A also shows an effective single-site probability with a globally reduced efficacy of selection, G 0 (σ / 2 N σ ˜ ) (short-dashed blue line).

Genetics

The only exemption being IL28B CC patients with cirrhosis, where a DAA-based regimen is considered the SOC by most guidelines due to a somewhat reduced efficacy of PegIFN and Rbv in these patients.

BioMed Research International

The use of a visual-tracking paradigm for attention assessment is based on the hypothesis that attention impairments in concussion patients are a consequence of reduced efficacy of predictive timing (Ghajar & Ivry, 2008).

Behavior Research Methods

The expression of these systems is a major cause of reduced efficacy of agricultural fungicides and herbicides [2], [3], and failure of chemotherapeutic treatment of tumours [4] [6] and infections by pathogenic microorganisms [7].

Plosone

Should this regulation occur in vivo, it would pose a medical problem of reduced efficacy of pharmaceutical IFN in inflamed tissues.

EMBO Molecular Medicine

Expert writing Tips

Best practice

When discussing the effectiveness of treatments or interventions, use "a reduced efficacy of" to clearly indicate a decline in their ability to produce the desired outcome. Ensure that the context clarifies what is experiencing reduced efficacy.

Common error

Avoid using "a reduced efficacy of" when you actually mean "efficiency", "effectiveness", or "effect". "Efficacy" specifically refers to the ability to produce a desired result under ideal conditions, while the other terms have broader meanings. For example, say "a reduced effect of the drug" rather than "a reduced efficacy of the drug" if you are referring to the drug's overall impact in real-world conditions.

Linguistic Context

The phrase "a reduced efficacy of" functions as a noun phrase that modifies another noun, typically describing something that has become less effective. Ludwig AI shows it frequently precedes nouns like "treatment", "medications", or "vaccination", specifying a decline in their effectiveness.

Expression frequency: Common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Encyclopedias

0%

Ludwig's WRAP-UP

In summary, the phrase "a reduced efficacy of" is a common and grammatically correct expression used to describe a decrease in the effectiveness of something, particularly in scientific and medical contexts. Ludwig AI indicates that it's frequently found in academic literature and used to report findings related to treatments, medications, or other interventions. When using this phrase, ensure that the context clearly identifies what is experiencing the reduction in efficacy. Alternative phrases like "a reduced potency of" or "a lower efficacy of" can be used depending on the specific nuance you wish to convey. While generally formal, it's crucial to distinguish "efficacy" from related terms like "efficiency" or "effect" to maintain precision in your writing.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

a lower efficacy of

Uses "lower" as a synonym of "reduced" before the word "efficacy".

a lowered efficacy of

Uses "lowered" as a synonym of "reduced" before the word "efficacy".

a decreased efficacy of

Uses "decreased" as a synonym of "reduced" before the word "efficacy".

a reduced potency of

Replaces "efficacy" with "potency", focusing on the strength or effectiveness of something.

a reduced efficiency of

Substitutes "efficacy" with "efficiency", highlighting the effectiveness relative to resources or effort.

a reduced impact of

Uses "impact" instead of "efficacy", focusing on the effect or influence of something.

a reduced validity of

Replaces "efficacy" with "validity", emphasizing the correctness or soundness of something.

a reduced effect of

Uses "effect" instead of "efficacy", broadly referring to the result or consequence of something.

a reduced usefulness of

Substitutes "efficacy" with "usefulness", highlighting the practical value of something.

a reduced performance of

Substitutes "efficacy" with "performance", highlighting the ability or capability of something.

FAQs

How can I use "a reduced efficacy of" in a sentence?

You can use "a reduced efficacy of" to describe a decrease in the effectiveness of something. For example, "The study showed "a reduced efficacy of" the vaccine against the new strain."

What's a good alternative to "a reduced efficacy of"?

Alternatives include phrases like "a lower efficacy of", "a reduced effect of", or "a decreased effectiveness of", depending on the specific context.

Is it better to say "reduced effectiveness" or "reduced efficacy"?

"Efficacy" specifically refers to the ability to produce a desired result under ideal conditions, while "effectiveness" refers to real-world conditions. Choose the term that best fits the context of your statement. You can also use alternative phrases like "a lower performance of".

What factors might cause "a reduced efficacy of" a treatment?

Factors can include drug resistance, changes in disease characteristics, patient-specific factors, or interactions with other medications. You can also consider external conditions or scenarios that may impact effectiveness.