a profound alteration

USAGE SUMMARY

The phrase "a profound alteration" is correct and usable in written English.
It can be used to describe a significant or deep change in a situation, condition, or object. Example: "The new policy led to a profound alteration in the way the company operates, affecting all departments."

✓ Grammatically correct

Science

News & Media

Encyclopedias

Human-verified examples from authoritative sources

Exact Expressions

34 human-written examples

But it's also about a profound alteration that these scientists wrought in the way we look at reality.

The New York Times

But only one book had such a decisive impact that I can date to it a profound alteration in my worldview and even behaviour.

The Guardian - Opinion

This state of development required a profound alteration in the genetic template to produce short pelvic blades, a forward-pointing big toe (adducted hallux), and other bipedal traits.

Encyclopedia Britannica

Paget Disease of the bone is a metabolic disorder which leads to a profound alteration of the bone's architecture.

Radiography

Overall, cannabis may provoke a profound alteration in brain neurotransmission and, in particular, in the mesolimbic system, where it can rearrange the molecular architecture at the synaptic level.

Neuropathology of Drug Addictions and Substance Misuse Volume 1: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids and Opioids

Its implementation caused a profound alteration in regional and urban systems, dividing the new State into two entities, the Federation of Bosnia and Herzegovina (FBiH) – Croat and Bosniak majority – and the Republika Srpska (RS) – Serb majority.

Cities

Human-verified similar examples from authoritative sources

Similar Expressions

26 human-written examples

His findings do not require any profound alteration in the way the French are viewed, namely as a people whose behavior in sum was deeply flawed and who are resistant to admitting those flaws.

The New York Times - Books

In four exocyst mutant lines with the most severe root growth defects (exo84b-1, sec8-3, sec8-4, and sec8-4 exo70A1), we predicted a more profound alteration in the distribution/pattern of DR5 expression if the exocyst mutant's slower root growth was due to a defect in auxin response in the stem cell niche or MZ.

BMC Plant Biology

Thus, even if DeGrazia is right that loss of numerical identity does not automatically follow from loss of personhood, it is certainly possible, and perhaps even likely, on the psychological view of our identity, that a transformation of a person into a nonperson would involve such a profound psychological alteration as to result in a numerically new being.

SEP

Rather, they suggest a profound metabolic alteration that needs to be taken into account if we are to understand fully the deleterious physical consequences of repeated use of this drug.

Appetite

A major finding in our studies is the unexpected profound alteration of signaling pathways in monocytes from patients treated with tremelimumab.

Plosone

Expert writing Tips

Best practice

Use "a profound alteration" to describe changes that are not only significant in scale but also deeply impact the fundamental nature of something. For example, "The discovery led to a profound alteration in our understanding of the universe."

Common error

Avoid using "a profound alteration" for minor or superficial changes. This phrase is best reserved for alterations that have deep and lasting effects. Instead, use "a slight change" or "a minor adjustment" for less impactful modifications.

Linguistic Context

The phrase "a profound alteration" functions as a noun phrase, typically serving as the object or subject complement within a sentence. It describes a significant or fundamental change, as seen in Ludwig examples where it refers to shifts in scientific understanding, genetic templates, or brain neurotransmission.

Expression frequency: Common

Frequent in

Science

76%

News & Media

18%

Encyclopedias

3%

Less common in

Formal & Business

0%

Wiki

0%

Reference

0%

Ludwig's WRAP-UP

In summary, the phrase "a profound alteration" is a noun phrase used to describe a significant and fundamental change. According to Ludwig AI, its usage is grammatically correct and particularly common in scientific and news contexts. It's best used to emphasize the depth and impact of a change, rather than superficial adjustments. For more informal settings, simpler alternatives may be more appropriate. When using the term remember that is more suited for formal or academic writing due to its sophisticated tone.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

a significant modification

Emphasizes the act of modifying something substantially, focusing on the change itself.

a deep transformation

Highlights the thorough and fundamental nature of the change, implying a complete shift.

a substantial change

Focuses on the magnitude of the change, indicating it is considerable and impactful.

a radical shift

Implies a complete departure from the original state, suggesting a fundamental change in direction or approach.

a fundamental restructuring

Stresses the reorganization of basic elements or structures, suggesting a deep systemic change.

a major adjustment

Focuses on the act of making significant corrections or modifications, emphasizing adaptation.

a sweeping reform

Suggests broad, extensive changes aimed at improvement or correction, often in a systematic way.

a complete overhaul

Implies a thorough and comprehensive renovation or reconstruction, leaving little of the original intact.

a sea change

Evokes a dramatic and fundamental transformation, often affecting attitudes, opinions, or societal norms.

a wholesale revision

Focuses on a complete and extensive review and amendment, indicating a thorough correction process.

FAQs

How can I effectively use "a profound alteration" in a sentence?

Use "a profound alteration" to describe a significant, deep, or fundamental change in something. For example, "The industrial revolution caused "a profound alteration" in societal structures".

What phrases can I substitute for "a profound alteration"?

You can use alternatives like "a significant change", "a deep transformation", or "a fundamental restructuring" depending on the context.

Is it appropriate to use "a profound alteration" in informal writing?

While grammatically correct, "a profound alteration" is more suited for formal or academic writing due to its sophisticated tone. In informal contexts, consider using simpler alternatives like "a big change" or "a major shift".

What distinguishes "a profound alteration" from "a simple change"?

"A profound alteration" implies a deep and significant change affecting fundamental aspects, while "a simple change" refers to a minor or superficial adjustment that doesn't drastically alter the essence of something.