a marked alteration

USAGE SUMMARY

The phrase "a marked alteration" is correct and usable in written English.
It can be used to describe a significant or noticeable change in something, often in contexts such as reports, analyses, or discussions about changes in data or conditions. Example: "The study revealed a marked alteration in the participants' behavior after the intervention."

✓ Grammatically correct

Science

Human-verified similar examples from authoritative sources

Similar Expressions

60 human-written examples

Notch3 knockout mice (Notch3−/−) show marked alteration of arterial SMCs, pointing to a critical role of Notch3 in the maturation and maintenance of arteries (Joutel, 2010a).

EMBO Molecular Medicine

Viewed in conjunction of the reports of Singh et al. [ 57], Suhail et al. [ 64], and Bedi and Priyanka [ 65], data from the present investigation reflect that DMBA induced marked alteration on renal functions as manifested by a significant increase in the kidney function markers, serum creatinine, urea, and uric acid.

BioMed Research International

In 1970, Haas showed marked alteration in growth direction and facial morphology as a result of orthopedic therapy [5].

Progress in Orthodontics

FurthermOverall quantify the degree tourhich hydrologic stanalysisty within the demonstrateser watersheds has been comarkedsed over four decalterationng a perind prior totaltectandeventmate-induced changes in rainflow patteregimes

Journal of Hydrology

The epigenetic factor, especially DNA methylation is the most important aspect of behavioral disorders with marked alteration in the DNA methylation pattern in the brain which leads to memory formation (Day & Sweatt, 2010).

Egyptian Journal of Forensic Sciences

Histologic examination showed marked alteration of the intestinal mucosa: erosions, villi depletion, and hemorrhagic infiltration.

Emerging Infectious Diseases

Notch3 knockout mice (Notch3−/−) showed marked alteration of arterial smooth muscle cells, but no GOM deposition.

EMBO Molecular Medicine

In our model, we detected marked alteration of both these proteins.

Cell Death and Disease

indica cultivars in which mPing can be efficiently mobilized and marked alteration in cytosine methylation of various types occurs.

BMC Plant Biology

Collectively, these findings indicate marked alteration in cardiac gene program in diabetic heart and therefore, augment the need to explore the modulators of gene expression in diabetic heart.

Cardiovascular Diabetology

As for the mesenchymal cell proliferation in the URS, the β-catenin GOF mutants did not display marked alteration at E11.5; however, cell proliferation was decreased at E13.5.

Cell Death and Differentiation

Expert writing Tips

Best practice

When describing changes, use "a marked alteration" to highlight that the modification is significant and easily noticeable. This phrase is particularly useful in scientific or technical contexts where precision is important.

Common error

While "a marked alteration" is appropriate for formal writing, avoid using it excessively in casual conversation or informal writing. Simpler phrases like "a big change" or "a noticeable difference" may be more suitable.

Linguistic Context

The phrase "a marked alteration" functions as a noun phrase, typically serving as the subject or object of a sentence. It signifies a notable or significant change. Based on Ludwig AI, this phrase is frequently encountered in describing experimental results, observations, or changes in conditions.

Expression frequency: Missing

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Ludwig's WRAP-UP

In summary, the phrase "a marked alteration" denotes a significant and noticeable change, particularly within formal and scientific contexts. Though Ludwig AI confirms its grammatical correctness and usability, its absence from the provided examples suggests it might be used less frequently or in highly specific scenarios. When aiming to express a notable shift, using this phrase can be particularly effective in reports and analyses where emphasizing the magnitude of change is crucial. Remember to consider the context to ensure the level of formality matches your intended audience and purpose.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

a significant modification

Replaces "alteration" with "modification" and "marked" with "significant", emphasizing the importance of the change.

a significant deviation

Combining "significant" and "deviation", this emphasizes both the importance and the departure from the norm of the change.

a noticeable difference

Shifts the focus to the difference observed rather than the act of altering, using "noticeable" as a more general descriptor.

a considerable variation

Substitutes "alteration" with "variation" and "marked" with "considerable", highlighting the extent of the change.

a distinct change

Uses "distinct" instead of "marked" to emphasize the clarity and recognizability of the change.

a substantial shift

Replaces "alteration" with "shift", suggesting a change in direction or focus, and "marked" with "substantial" to indicate magnitude.

a pronounced transformation

Employs "transformation" to convey a more dramatic alteration, with "pronounced" highlighting its clear visibility.

a striking deviation

Uses "deviation" to suggest a departure from a norm or standard, with "striking" emphasizing its impressiveness.

a clear divergence

Replaces "alteration" with "divergence", indicating a separation or moving apart, and "marked" with "clear" for emphasis.

a major adjustment

Substitutes "alteration" with "adjustment", implying a correction or adaptation, and "marked" with "major" to denote importance.

FAQs

How can I use "a marked alteration" in a sentence?

You can use "a marked alteration" to describe a significant change. For example, "The experiment showed "a marked alteration" in the patient's condition after the new treatment."

What's the difference between "a marked alteration" and "a slight change"?

"A marked alteration" implies a significant and noticeable change, whereas "a slight change" indicates a minor or subtle modification.

What are some alternatives to using "a marked alteration"?

You can use alternatives like "a significant change", "a noticeable difference", or "a considerable variation" depending on the specific context.

Is "a marked alteration" appropriate for formal writing?

Yes, "a marked alteration" is well-suited for formal writing, particularly in academic, scientific, or technical contexts where precise language is important.