a major response to

USAGE SUMMARY

The phrase "a major response to" is correct and usable in written English.
It can be used when discussing significant reactions or actions taken in reaction to a particular event, issue, or stimulus. Example: "The new policy was a major response to the growing concerns about climate change."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

17 human-written examples

Neither a steady drip of leaks detailing how MBS's inner circle was responsible for the gruesome killing nor global pressure on Riyadh for a major response to the assassination has convinced Saudi King Salman or President Donald Trump to cut him off.

HuffPost

That achievement reflects the step-by-step requirements of mounting a major response to an epidemic: Volunteers have to know that they'll be cared for if they contract the disease.

The Washington Post

The New York chapter of Working Families, a leftist group that has endorsed him, says it already has seen a major response to its organizing efforts for Sanders.

Los Angeles Times

TRG 1 3 scores were defined as a major response to chemoradiation.

Annals of Surgical Oncology

These lead to activation of NF-κB, which is a major response to TLRs.

Arthritis Research and Therapy

However, only a few patients show a major response to this drug, with a very modest effect on long-term survival.

British Journal of Cancer

Human-verified similar examples from authoritative sources

Similar Expressions

43 human-written examples

A second major response to proteasome inhibitors is activation of heat-shock factor 1 (HSF1), the master regulator of the heat-shock response, which increases levels of HSP70 and other protein chaperones.

eLife

The rescue to a major response seems to occur at a rate of 10%to15%5% among the various biologics.

Arthritis Research and Therapy

Due to the role of CMA as a major response pathway to oxidative stress, which is an established mediator of tissue damage in cystinosis, our results highlight CMA impairment as an important pathogenic factor in CTNS deficiency.

EMBO Molecular Medicine

A major response of cells to Hedgehog (Hh) signaling is the upregulation of transcription of specific target genes.

Biology Open

A major response of cells to hypoxia is the induction of hypoxia-inducible factor 1 (HIF1), which is associated with tumour progression and metastasis (Liao et al, 2007).

British Journal of Cancer

Expert writing Tips

Best practice

When using "a major response to", ensure that the response is appropriately scaled to the initial action or event. Overstating the significance of the response can undermine its impact.

Common error

Avoid using "a major response to" for minor issues. Reserve it for situations where the reaction is substantial and consequential.

Linguistic Context

The phrase "a major response to" functions as a noun phrase that describes a significant action or reaction taken as a consequence of something. Ludwig examples show its use in diverse contexts, such as responses to DNA damage, environmental stress, or policy issues.

Expression frequency: Common

Frequent in

Science

50%

News & Media

37%

Formal & Business

6%

Less common in

Academia

3%

Wiki

2%

Reference

2%

Ludwig's WRAP-UP

In summary, the phrase "a major response to" is a grammatically sound and commonly used expression to describe a substantial reaction to a particular event or issue. As Ludwig AI indicates, it’s deemed correct. It appears most frequently in scientific and news contexts, suggesting a neutral to formal register. When using this phrase, ensure the scale of the response matches the significance of the initial event. Consider alternatives like "a significant reaction to" or "a considerable reply to" to vary your language. Ludwig examples demonstrate the phrase's versatility across different fields, further solidifying its acceptability and usefulness in various writing scenarios.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

a significant reaction to

Emphasizes the importance of the reaction.

a substantial answer to

Highlights the extensiveness of the reply.

a considerable reply to

Focuses on the noteworthiness of the reply.

a notable reaction to

Highlights the remarkableness of the reaction.

a strong reply to

Emphasizes the forcefulness of the reply.

an important reaction to

Highlights the relevance of the reaction.

a critical solution to

Indicates the cruciality of the resolution.

a key measure for

Emphasizes the centrality of the step.

a vital action against

Highlights the indispensability of the measure.

a principal counter to

Focuses on the leading defense against.

FAQs

How can I use "a major response to" in a sentence?

You can use "a major response to" to describe a significant action or reaction that addresses a particular issue. For example, "The government's new policy is "a major response to" rising unemployment rates."

What can I say instead of "a major response to"?

You can use alternatives like "a significant reaction to", "a substantial answer to", or "a considerable reply to" depending on the context.

Which is correct, "a major response to" or "a major reaction to"?

Both "a major response to" and "a major reaction to" are correct and largely interchangeable. The choice depends on whether you want to emphasize the action taken (response) or the feeling/opinion expressed (reaction).

What's the difference between "a major response to" and "a minor response to"?

"A major response to" indicates a significant and impactful reaction, while "a minor response to" implies a smaller, less influential reaction. The choice depends on the scale and importance of the action taken.