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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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a large alignment

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "a large alignment" is correct and usable in written English.
It can be used in contexts where you are referring to a significant or extensive arrangement or positioning of elements, such as in data analysis, project management, or design. Example: "The team achieved a large alignment of goals across all departments, ensuring everyone was working towards the same objectives."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

7 human-written examples

Multigene concatenation proposes that phylogenetic analysis should always be performed using all available character data, essentially sticking many aligned genes together to give a large alignment.

Because ML phylogenetic inference is NP complete [6], no practical method can guarantee that it will find the optimal topology for a large alignment.

Science

Plosone

To reduce the cost resulting from a large alignment target, many algorithms have been developed that rapidly reduce the size of the search target for aligning a given read.

Science

Plosone

The authors then proceed to identify sets of mutations that might be suitable drug targets, through an analysis of covariation in a large alignment of HIV sequences.

We found a large alignment between CardioNet and both mitochondrial networks with 90.48% and 92.49% of the mitochondrial network reactions are represented in CardioNet.

(B ) Observed vs predicted accuracies in an independent data set of variable length alignments for 7047 pdb chains (Supplementary file 3 ), using maximum number of sequences obtained with HHblits as opposed to subsampling a large alignment.

Science

eLife
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Human-verified similar examples from authoritative sources

Similar Expressions

53 human-written examples

A larger alignment of 831 CarD sequences is included (Source code 1 ).

Science

eLife

After every sequence has been either placed in an alignment or placed as a "singleton," the individual alignments are then profiled to a larger alignment.

We expect that a more efficient pairwise potential optimization algorithm that can search a larger alignment space will further improve the alignment accuracy.

This region of sequence divergence is also observed in a larger alignment  [ 10] of EF-Tu molecules from Gram-negative organisms (data not shown).

– Given a polynomial time algorithm for finding a largest alignment of RMSD below a threshold d, one can efficiently compute an alignment of a given size ℓ which minimizes the RMSD (Theorem 7).

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Expert writing Tips

Best practice

When using "a large alignment", specify the context and what elements are being aligned. This provides clarity and avoids ambiguity.

Common error

Avoid using "a large alignment" without quantifying or specifying its characteristics. Instead of saying "we need a large alignment", be specific: "we need a large alignment of genomic sequences to improve phylogenetic analysis".

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

83%

Authority and reliability

4.1/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "a large alignment" functions primarily as a noun phrase. It typically acts as a subject or object within a sentence, denoting a significant or extensive arrangement of elements, often within a scientific or technical context, as shown in Ludwig's examples.

Expression frequency: Uncommon

Frequent in

Science

83%

News & Media

9%

Formal & Business

8%

Less common in

Academia

0%

Encyclopedias

0%

Wiki

0%

Ludwig's WRAP-UP

In summary, "a large alignment" is a grammatically correct noun phrase typically used in formal and scientific contexts to describe a significant arrangement of data, sequences, or other elements. As Ludwig AI indicates, the phrase is perfectly acceptable in English writing. The most frequent use of "a large alignment" is within scientific literature. When using this phrase, it's important to provide context to what is being aligned. Alternatives such as "an extensive alignment" or "a significant alignment" can be used for similar meanings, but they highlight slightly different aspects of the alignment.

FAQs

How is "a large alignment" typically used in scientific writing?

In scientific contexts, "a large alignment" refers to a substantial arrangement of sequences (DNA, protein, etc.) used for comparative analysis. It's often essential for phylogenetic studies or identifying conserved regions.

What are some alternatives to using "a large alignment"?

You can use alternatives like "an extensive alignment", "a significant alignment", or "a substantial alignment" depending on the specific nuance you want to convey.

In data analysis, what does it mean to have "a large alignment"?

In data analysis, "a large alignment" usually implies a dataset where multiple variables or datasets are arranged in a way that facilitates comparison and pattern identification. The scale allows for more robust conclusions.

What factors determine whether an alignment is considered "large"?

The criteria for what constitutes "large" can vary. It often depends on the specific field, the typical scale of analyses, and the computational resources available. In genomics, for example, a "large" alignment might involve thousands of sequences or millions of base pairs.

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Source & Trust

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Authority and reliability

4.1/5

Expert rating

Real-world application tested

Most frequent sentences: