a broad modification in

USAGE SUMMARY

The phrase "a broad modification in" is correct and usable in written English.
It can be used when discussing significant changes or alterations in a particular area or aspect. Example: "The study revealed a broad modification in the participants' behavior after the intervention."

✓ Grammatically correct

Science

News & Media

Human-verified similar examples from authoritative sources

Similar Expressions

60 human-written examples

We operationally define a peak as a broad modification if it is >50 kb in extent.

BMC Genomics

We operationally defined a broad modification as >50 kb in length.

BMC Genomics

In this region, we found a broad modification (H3K9me3+) in B73 cells but not in B12 cells.

BMC Genomics

We establish the transcriptional relevance of a difference in an H3K9me3+ broad modification in that it affected transcription of CACNG7.

BMC Genomics

(4) We detected significant and clear changes in broad modification areas for H3K27me3 and, to a lesser extent, for H3K9me3, implying that the processes creating or maintaining these broad modifications differed in activity among cell types; in one case we verified that this change in a broad modification affected gene expression.

BMC Genomics

We verified that a change in a broad modification affected gene expression of CACNG7.

BMC Genomics

Only regions that clearly displayed extended broad peaks that differed among cell types were considered to show a broad modification difference.

BMC Genomics

The Justice Department praised the decision to block the law for 2012 and welcomed "the court's agreement that South Carolina's law required broad modification in order to respond to the serious concerns raised by the attorney general that the law as written would exclude minority voters".

The New York Times

We use the term "broad modification" to denote long regions of chromosomal space in which there is a given epigenetic modification present continuously (>50 kb), as opposed to focal regions of modification ("peaks") in a promoter or other region.

BMC Genomics

We detected differences among cell types in broad modification regions for H3K27me3 in many of the more lengthy regions that were tiled in this array format.

BMC Genomics

Do we observe differences in broad modifications among BTSC types and neural stem cells?

BMC Genomics

Expert writing Tips

Best practice

Use "a broad modification in" to describe significant changes or alterations, especially when discussing processes, systems, or policies.

Common error

Avoid using "a broad modification in" in casual conversation or informal writing. Opt for simpler phrases like "a big change in" or "a major adjustment to" for better clarity and appropriateness.

Linguistic Context

The phrase "a broad modification in" functions as a prepositional phrase, often acting as an adjective modifying a noun. It indicates the scope or extent of a change or alteration within a particular system, area, or context, as shown in the Ludwig examples.

Expression frequency: Missing

Frequent in

Science

33%

News & Media

33%

Formal & Business

33%

Less common in

Academia

0%

Encyclopedias

0%

Wiki

0%

Ludwig's WRAP-UP

In summary, the phrase "a broad modification in" denotes a significant and extensive alteration within a specified domain. Ludwig AI indicates the phrase is grammatically correct and suitable for formal and scientific contexts. Given its descriptive nature, it serves to emphasize the scope and impact of the change. While versatile, it is most appropriately used in professional or scientific writing. Alternatives such as "a significant change in" or "a wide-ranging alteration in" can be used to similar effect.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

a significant alteration in

Replaces "broad" with "significant", emphasizing the importance of the change.

a major shift in

Substitutes "modification" with "shift", highlighting a change in direction or focus.

a wide-ranging change in

Replaces "broad modification" with "wide-ranging change", stressing the extent of the alteration.

a substantial adjustment to

Uses "substantial adjustment" instead of "broad modification", focusing on the degree of change.

a comprehensive revision of

Employs "comprehensive revision", indicating a thorough and complete alteration.

a sweeping transformation in

Replaces "modification" with "transformation", conveying a more dramatic change.

a fundamental alteration to

Uses "fundamental alteration", emphasizing the basic or essential nature of the change.

a marked difference in

Substitutes "broad modification" with "marked difference", focusing on a noticeable variation.

a considerable change to

Replaces "broad modification" with "considerable change", stressing the magnitude of the alteration.

a large-scale alteration in

Employs "large-scale alteration", emphasizing the extensive nature of the change.

FAQs

How can I use "a broad modification in" in a sentence?

You can use "a broad modification in" to describe substantial changes or alterations within a specific context. For example: "The study revealed "a broad modification in" the participants' behavior after the intervention".

What are some alternatives to "a broad modification in"?

You can use alternatives like "a significant change in", "a wide-ranging alteration in", or "a major shift in" depending on the specific context and nuance you wish to convey.

Which is correct, "a broad modification in" or "a broad modification to"?

"A broad modification in" and "a broad modification to" can both be correct, but they have slightly different meanings. "In" often refers to a system or area, while "to" refers to adapting or adjusting something toward a specific purpose.

What's the difference between "a broad modification in" and "a minor change in"?

"A broad modification in" implies a significant and extensive alteration, whereas "a minor change in" suggests a small or insignificant adjustment.