Increased triglycerides and decreased high-density lipoprotein, as main components of MS, were apparent in young AMI patients.
There has been a recent report showing that female AMI patients aged younger than 40 years have a higher long-term mortality rate than their male counterparts after PCI, 24 suggesting that the effectiveness of PCI in young AMI patients is sex-related.
In a cohort of 102 patients suffering from myocardial infarction below the age of 40 and 200 matched controls, large and intermediate HDL was inversely correlated with premature AMI, while small HDL was higher in young AMI patients but statistical significance was lost after adjustment [30].
Eventually, with little more than 100 pages to go, we get to the younger Amis and Powell's briskly dismissive assessment that 'the swagger of Martin the child, as of Martin the writer, is a far wobblier affair than it at first appears'.
The two young women, Ami and Yumi, are Japanese.
Few studies have compared mortality rates in young patients with AMI with those in the general population.
Given the much lower mortality in this age group in the general population, young survivors of AMI, particularly women, remain at a much higher risk of death, much of this, however, due to non-CVD causes.
2 27 However, in developing countries, addressing the aforementioned disparities in disease awareness, 28 recognition and timely administration of evidence-based therapies could lead to meaningful improvements in the care of young women with AMI and should be a target of future interventions.
For the last 5-year period, the standardised mortality ratio for young survivors of AMI compared with the general population was 4.34 (95% CI 3.04 to 5.87) and 2.43 (95% CI 2.12 to 2.76) for men aged 25 44 and 45 54 years, respectively, and 13.53 (95% CI 8.36 to 19.93) and 6.42 (95% CI 5.24 to 7.73) for women, respectively.
The gradient across deprivation categories for male incidence in 1990 92 was most pronounced at younger ages; RR of AMI in the most deprived areas compared to the least was 2.6 (95% CI: 1.6 4.3) for those aged 45 59 years and 1.6 (1.1 2.5) at 60 74 years.
