Sentence examples for yields potent from inspiring English sources

This strategy yields potent inhibitors of Abeta aggregation and could lead to therapeutics for Alzheimer's disease and other forms of neurodegeneration.

We describe herein for the first time the use of functionalized sulfonamides as a design and diversity element which, when coupled to the 1,2,5-thiadiazolidin-3-one 1,2,5-thiadiazolidin-3-one 1,2,5-thiadiazolidin-3-one 1,2,5-thiadiazolidin-3-one 1,1s human leukocyte elastase (HLE), proteinase 3 (PR 3) andioxidepscaffoldt G).

In ex vivo isolated liver perfusion and liver transplantation models exogenously added CO yields potent cytoprotective effects [ 14- 16].

Small-molecule screening and subsequent optimization have yielded potent and specific activators and inhibitors of this process.

However, when crushed, the tablets yielded potent quantities of drug that could be snorted, injected, or swallowed to produce a powerful high.

Structure guided optimization effort yielded potent and stable 11β-HSD1 selectinhibitoritor 42.

Presented Vietnamese style — with lettuce, chiles and mint for bundling, and nuoc cham, tempered with Meyer lemon, for dunking — they yield potent, gratifying handfuls.

To yield potent inhibitors of beta-amyloid (Abeta) aggregation, we synthesized small molecules that increase their steric bulk by binding to chaperones but also have a moiety available for interaction with Abeta.

On the other hand, the modification within a multi-Leu core in combination with the incorporation of a C-terminal 4-amidinobenzylamide (Amba) residue yielded potent cyclic analogues.

Synthesis of focused indole and azaindole analogs yielded potent and selective 5-azaindole Cdc7 inhibitors with improved intrinsic metabolic stability (ie 36).

We describe an optimized series of acyclic hydroxyethylamine transition state isosteres of β-secretase that incorporates a variety of P2 side chains that yield potent inhibitors with excellent cellular activity.